Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 184983..185632 Replicon chromosome
Accession NZ_LR746496
Organism Acididesulfobacillus acetoxydans isolate PacBioINE

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MNU25_RS00815 Protein ID WP_240983337.1
Coordinates 184983..185405 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MNU25_RS00820 Protein ID WP_240983338.1
Coordinates 185402..185632 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNU25_RS00790 (DEACI_0161) 180624..181376 - 753 WP_240983333.1 5-oxoprolinase subunit PxpA -
MNU25_RS00795 181948..182058 - 111 Protein_154 hypothetical protein -
MNU25_RS00800 (DEACI_0163) 182075..183283 - 1209 WP_240983334.1 threonine ammonia-lyase -
MNU25_RS00805 (DEACI_0164) 183300..183689 - 390 WP_277350653.1 RidA family protein -
MNU25_RS00810 (DEACI_0165) 183854..184750 - 897 WP_240983336.1 transcriptional regulator -
MNU25_RS00815 (DEACI_0166) 184983..185405 - 423 WP_240983337.1 type II toxin-antitoxin system VapC family toxin Toxin
MNU25_RS00820 (DEACI_0167) 185402..185632 - 231 WP_240983338.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
MNU25_RS00825 (DEACI_0168) 185824..185997 - 174 Protein_160 DUF979 family protein -
MNU25_RS00830 (DEACI_0169) 185982..186392 - 411 WP_240983339.1 DUF969 family protein -
MNU25_RS00835 (DEACI_0170) 186380..187324 - 945 WP_261487033.1 biotin-dependent carboxyltransferase family protein -
MNU25_RS00840 (DEACI_0171) 187339..188043 - 705 WP_240983341.1 5-oxoprolinase subunit PxpB -
MNU25_RS00845 (DEACI_0173) 188371..189141 - 771 WP_240983342.1 HD-GYP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15422.92 Da        Isoelectric Point: 5.6159

>T289056 WP_240983337.1 NZ_LR746496:c185405-184983 [Acididesulfobacillus acetoxydans]
MKYMLDTNICVYLIKKKPENVLITLHSNMGDGVAISAITLAELMHGVEASAYPERNALALNQFLSITDILPFDHEAAAEY
GKICAALRRRGIPIGAMDMLIAAHAKAKGLIVVTNNVREFERVEGLEVENWVSENKPSDL

Download         Length: 423 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8776.88 Da        Isoelectric Point: 4.7228

>AT289056 WP_240983338.1 NZ_LR746496:c185632-185402 [Acididesulfobacillus acetoxydans]
VETAKLFINGQSQAVRLPKEYRFSGSEVYIQKVGNTVMLFPKERVWETFLQGLNSFTDDFFAEERDGGVQVQRETL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References