288979

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/-
Location 55560..55936 Replicon plasmid paAPEC5202
Accession NZ_LR740759
Organism Escherichia coli strain BEN5202 isolate laying hen 51 weeks old

Toxin (Protein)


Gene name parE Uniprot ID A0A075MDK3
Locus tag APEC5202_RS25205 Protein ID WP_000969988.1
Coordinates 55754..55936 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag APEC5202_RS25200 Protein ID WP_001324224.1
Coordinates 55560..55757 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APEC5202_RS25185 51094..51345 + 252 WP_077695279.1 colicin V family bacteriocin -
APEC5202_RS25190 51515..53629 - 2115 WP_001183604.1 peptidase domain-containing ABC transporter -
APEC5202_RS25195 53604..54878 - 1275 WP_000489608.1 HlyD family secretion protein -
APEC5202_RS25200 55560..55757 + 198 WP_001324224.1 toxin-antitoxin system protein Antitoxin
APEC5202_RS25205 55754..55936 + 183 WP_000969988.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APEC5202_RS25210 56035..56343 + 309 WP_000377483.1 hypothetical protein -
APEC5202_RS25215 56903..57937 + 1035 WP_001190233.1 3-deoxy-7-phosphoheptulonate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid tet(B) / sitABCD vat / iroN / iroE / iroD / iroC / iroB / iucA / iucB / iucC / iucD / iutA 1..223939 223939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6931.07 Da        Isoelectric Point: 4.5349

>T288979 WP_000969988.1 NZ_LR740759:55754-55936 [Escherichia coli]
MMEIFWTMLASQDRKRIREYIAEQNLIAAIELDERIGCSASLLFSLSFISVQVHDNIITV

Download         Length: 183 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7658.53 Da        Isoelectric Point: 7.2046

>AT288979 WP_001324224.1 NZ_LR740759:55560-55757 [Escherichia coli]
MDRNGSQLIRDFMRQTVERQHNTWFRDQVEAGRQQLERGDVLPHDMVESSAAAWRDEMSRKVAGK

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A075MDK3

Antitoxin

Source ID Structure

References