Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK(toxin)
Location 3207529..3208093 Replicon chromosome
Accession NZ_LR738849
Organism Desulfovibrio sp. 86

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag DESU86_RS13160 Protein ID WP_179981445.1
Coordinates 3207529..3207852 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DESU86_RS13165 Protein ID WP_179981446.1
Coordinates 3207839..3208093 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DESU86_RS13145 3202686..3203423 + 738 WP_179981442.1 DotI/IcmL/TraM family protein -
DESU86_RS13150 3203423..3206401 + 2979 WP_179981443.1 type IV secretion protein IcmB -
DESU86_RS13155 3206398..3207498 + 1101 WP_179981444.1 hypothetical protein -
DESU86_RS13160 3207529..3207852 - 324 WP_179981445.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DESU86_RS13165 3207839..3208093 - 255 WP_179981446.1 hypothetical protein Antitoxin
DESU86_RS13170 3208182..3210230 + 2049 WP_179981447.1 DotA/TraY family protein -
DESU86_RS13175 3210233..3210673 + 441 WP_179981448.1 hypothetical protein -
DESU86_RS13180 3210641..3210943 - 303 WP_179981449.1 hypothetical protein -
DESU86_RS13185 3210933..3211715 - 783 WP_179981450.1 ParA family protein -
DESU86_RS13190 3211849..3212319 + 471 WP_179981451.1 DotD/TraH family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3196477..3262136 65659


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-103)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11394.48 Da        Isoelectric Point: 8.9354

>T288928 WP_179981445.1 NZ_LR738849:c3207852-3207529 [Desulfovibrio sp. 86]
MQRGEVWWVNFDPSQGMEIQKCRPAVILTVNALNKARGTVVVVPLSTSAKPRPPIVVPLDSAGAGSVAVCDQLCAADKKR
FGKKLCDLSAADLATLTESMKIVLGLM

Download         Length: 324 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9408.73 Da        Isoelectric Point: 4.3431

>AT288928 WP_179981446.1 NZ_LR738849:c3208093-3207839 [Desulfovibrio sp. 86]
MQLLLHIPDPIAERFKQTVPARQRSAYVADLLEKALPVENDPLYLIALEVEQDAVLNAEMQEWRDALMTDGIRGEEVGGA
HAAR

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References