Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1918467..1919082 Replicon chromosome
Accession NZ_LR738724
Organism Streptococcus suis isolate 9401240

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GPW69_RS09280 Protein ID WP_171841470.1
Coordinates 1918467..1918802 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GPW69_RS09285 Protein ID WP_074391634.1
Coordinates 1918795..1919082 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPW69_RS09260 1913712..1915055 - 1344 WP_074391637.1 cysteine--tRNA ligase -
GPW69_RS09270 1915325..1915942 - 618 WP_015647409.1 serine O-acetyltransferase -
GPW69_RS09275 1915996..1918215 - 2220 WP_074391636.1 polyribonucleotide nucleotidyltransferase -
GPW69_RS09280 1918467..1918802 - 336 WP_171841470.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
GPW69_RS09285 1918795..1919082 - 288 WP_074391634.1 hypothetical protein Antitoxin
GPW69_RS09290 1919396..1919665 - 270 WP_002938849.1 30S ribosomal protein S15 -
GPW69_RS09295 1919868..1921145 - 1278 WP_074391633.1 NCS2 family nucleobase:cation symporter -
GPW69_RS09300 1921364..1921837 - 474 WP_074391632.1 hypothetical protein -
GPW69_RS09305 1921818..1922036 - 219 WP_074391631.1 helix-turn-helix transcriptional regulator -
GPW69_RS09310 1922190..1922699 - 510 WP_044758680.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12849.88 Da        Isoelectric Point: 9.1835

>T288926 WP_171841470.1 NZ_LR738724:c1918802-1918467 [Streptococcus suis]
MDKYQVNLPLAIYEELADIRSYIREELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGQLVPGQLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10655.41 Da        Isoelectric Point: 4.5425

>AT288926 WP_074391634.1 NZ_LR738724:c1919082-1918795 [Streptococcus suis]
MALTAKKKLINFQSEKSLVEEAKVVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFAELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References