Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 134001..134632 Replicon plasmid 4
Accession NZ_LR723673
Organism Rhizobium flavum strain YW14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFD27_RS22465 Protein ID WP_077548347.1
Coordinates 134231..134632 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFD27_RS22460 Protein ID WP_077548346.1
Coordinates 134001..134231 (+) Length 77 a.a.

Genomic Context

GFD27_RS22440GFD27_RS22445GFD27_RS22450GFD27_RS22460GFD27_RS22465GFD27_RS22470GFD27_RS22475GFD27_RS22480GFD27_RS22485GFD27_RS22455
Location: 130339..131214 (876 bp)
Type: Others
Protein ID: WP_077548342.1
Location: 131244..131999 (756 bp)
Type: Others
Protein ID: WP_172977952.1
Location: 132034..132870 (837 bp)
Type: Others
Protein ID: WP_077548344.1
Location: 134001..134231 (231 bp)
Type: Antitoxin
Protein ID: WP_077548346.1
Location: 134231..134632 (402 bp)
Type: Toxin
Protein ID: WP_077548347.1
Location: 135360..136940 (1581 bp)
Type: Others
Protein ID: WP_077548607.1
Location: 137344..137736 (393 bp)
Type: Others
Protein ID: Protein_134
Location: 138014..138742 (729 bp)
Type: Others
Protein ID: WP_036588740.1
Location: 138924..139082 (159 bp)
Type: Others
Protein ID: WP_172977951.1
Location: 132925..133818 (894 bp)
Type: Others
Protein ID: WP_077548345.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GFD27_RS22440130339..131214+876WP_077548342.1amino acid ABC transporter permease-
GFD27_RS22445131244..131999+756WP_172977952.1amino acid ABC transporter ATP-binding protein-
GFD27_RS22450132034..132870+837WP_077548344.1ABC transporter substrate-binding protein-
GFD27_RS22455132925..133818-894WP_077548345.1LysR family transcriptional regulator-
GFD27_RS22460134001..134231+231WP_077548346.1antitoxinAntitoxin
GFD27_RS22465134231..134632+402WP_077548347.1tRNA(fMet)-specific endonuclease VapCToxin
GFD27_RS22470135360..136940+1581WP_077548607.1ISL3-like element ISRsp8 family transposase-
GFD27_RS22475137344..137736+393Protein_134transposase-
GFD27_RS22480138014..138742+729WP_036588740.1FadR family transcriptional regulator-
GFD27_RS22485138924..139082+159WP_172977951.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid--1..150934150934
-flankIS/Tn--135687..1369401253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15054.16 Da        Isoelectric Point: 7.2442

>T288868 WP_077548347.1 NZ_LR723673:134231-134632 [Rhizobium flavum]
VLKYMLDTNICIFTIKNRPEQVREAFNRFHDQLCISSVSFMELIYGAEKSASPEKNFPVVEGFAARLEVLAYDEPAASHT
GQLRAELARNGTPIGPYDALIAGHARSRGLIMVTNNRREFDRVPGLRVEDWTR

Download         Length: 402 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8327.40 Da        Isoelectric Point: 5.0166

>AT288868 WP_077548346.1 NZ_LR723673:134001-134231 [Rhizobium flavum]
MEQGAVFQSNRSQAIRLPKAVALPDDVKRVDIVAVGRTRIIAPAGEVWDSWFEGAAATADFMSERDQPASQKREAL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References