Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 134001..134632 Replicon plasmid 4
Accession NZ_LR723673
Organism Rhizobium flavum strain YW14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFD27_RS22465 Protein ID WP_077548347.1
Coordinates 134231..134632 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFD27_RS22460 Protein ID WP_077548346.1
Coordinates 134001..134231 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFD27_RS22440 130339..131214 + 876 WP_077548342.1 amino acid ABC transporter permease -
GFD27_RS22445 131244..131999 + 756 WP_172977952.1 amino acid ABC transporter ATP-binding protein -
GFD27_RS22450 132034..132870 + 837 WP_077548344.1 ABC transporter substrate-binding protein -
GFD27_RS22455 132925..133818 - 894 WP_077548345.1 LysR family transcriptional regulator -
GFD27_RS22460 134001..134231 + 231 WP_077548346.1 antitoxin Antitoxin
GFD27_RS22465 134231..134632 + 402 WP_077548347.1 tRNA(fMet)-specific endonuclease VapC Toxin
GFD27_RS22470 135360..136940 + 1581 WP_077548607.1 ISL3-like element ISRsp8 family transposase -
GFD27_RS22475 137344..137736 + 393 Protein_134 transposase -
GFD27_RS22480 138014..138742 + 729 WP_036588740.1 FadR family transcriptional regulator -
GFD27_RS22485 138924..139082 + 159 WP_172977951.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..150934 150934
- flank IS/Tn - - 135687..136940 1253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15054.16 Da        Isoelectric Point: 7.2442

>T288868 WP_077548347.1 NZ_LR723673:134231-134632 [Rhizobium flavum]
VLKYMLDTNICIFTIKNRPEQVREAFNRFHDQLCISSVSFMELIYGAEKSASPEKNFPVVEGFAARLEVLAYDEPAASHT
GQLRAELARNGTPIGPYDALIAGHARSRGLIMVTNNRREFDRVPGLRVEDWTR

Download         Length: 402 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8327.40 Da        Isoelectric Point: 5.0166

>AT288868 WP_077548346.1 NZ_LR723673:134001-134231 [Rhizobium flavum]
MEQGAVFQSNRSQAIRLPKAVALPDDVKRVDIVAVGRTRIIAPAGEVWDSWFEGAAATADFMSERDQPASQKREAL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References