Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-parD/VapC-CC2985
Location 3877921..3878723 Replicon chromosome
Accession NZ_LR723670
Organism Rhizobium flavum strain YW14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFD27_RS18950 Protein ID WP_077548946.1
Coordinates 3877921..3878343 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GFD27_RS18955 Protein ID WP_077548945.1
Coordinates 3878469..3878723 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFD27_RS18925 3873463..3873780 - 318 WP_077548950.1 L-rhamnose mutarotase -
GFD27_RS18930 3873792..3874844 - 1053 WP_172977877.1 Gfo/Idh/MocA family oxidoreductase -
GFD27_RS18935 3875030..3875986 + 957 WP_172977909.1 LacI family DNA-binding transcriptional regulator -
GFD27_RS18940 3876253..3876852 - 600 Protein_3725 hypothetical protein -
GFD27_RS18945 3877670..3877924 + 255 WP_077548947.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GFD27_RS18950 3877921..3878343 + 423 WP_077548946.1 type II toxin-antitoxin system VapC family toxin Toxin
GFD27_RS18955 3878469..3878723 + 255 WP_077548945.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GFD27_RS18960 3878723..3879016 + 294 WP_077548944.1 type II toxin-antitoxin system RelE/ParE family toxin -
GFD27_RS18965 3879153..3879851 + 699 WP_077548943.1 IS6 family transposase -
GFD27_RS18970 3879878..3880204 + 327 WP_172977878.1 EAL domain-containing protein -
GFD27_RS18975 3880224..3880886 - 663 WP_077548941.1 ankyrin repeat domain-containing protein -
GFD27_RS18980 3880883..3881176 - 294 WP_077548940.1 DUF1311 domain-containing protein -
GFD27_RS18985 3881688..3881951 - 264 WP_077548939.1 hypothetical protein -
GFD27_RS18990 3882465..3883001 - 537 WP_139346292.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-125)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15731.93 Da        Isoelectric Point: 6.7219

>T288866 WP_077548946.1 NZ_LR723670:3877921-3878343 [Rhizobium flavum]
MRYLLDTNVVSELRKVGDGKADQNVTAWISAQDSRDLYISAITILELERGILSIQRRDIEQGARLRAWMDSRVRPEFAQR
IVAIDEAIATRCAHLHIPDRRNEADALIAATAVVHGLVVVTRNTQDFQGTGVILVDPWRS

Download         Length: 423 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9471.69 Da        Isoelectric Point: 9.7747

>AT288866 WP_077548945.1 NZ_LR723670:3878469-3878723 [Rhizobium flavum]
MATMNVSLPDPMKDWVEAQAKTGRYSNVSDYVRDLIRRDQARTHKIAQMQRFVDDGITSGLGRRSKDELFAAATELAEIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References