Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 132124..132722 Replicon chromosome
Accession NZ_LR699115
Organism Aquicella lusitana strain SGT-39

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag AQUSIP_RS10670 Protein ID WP_114834773.1
Coordinates 132402..132722 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag AQUSIP_RS10665 Protein ID WP_114834774.1
Coordinates 132124..132387 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AQUSIP_RS10645 127552..128136 + 585 WP_114834779.1 YceI family protein -
AQUSIP_RS10650 128269..129054 + 786 WP_170131838.1 alpha/beta hydrolase -
AQUSIP_RS10655 129479..131023 - 1545 WP_114834776.1 hypothetical protein -
AQUSIP_RS10660 131071..131895 - 825 WP_147277496.1 hypothetical protein -
AQUSIP_RS10665 132124..132387 + 264 WP_114834774.1 hypothetical protein Antitoxin
AQUSIP_RS10670 132402..132722 + 321 WP_114834773.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
AQUSIP_RS10675 132732..133820 - 1089 WP_114834772.1 PA0069 family radical SAM protein -
AQUSIP_RS10680 133832..135076 - 1245 WP_114834771.1 Y-family DNA polymerase -
AQUSIP_RS10685 135080..135592 - 513 WP_114834770.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
AQUSIP_RS10690 135888..137078 + 1191 WP_114834769.1 multidrug effflux MFS transporter -
AQUSIP_RS10695 137094..137708 - 615 WP_147277495.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-104)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11612.51 Da        Isoelectric Point: 9.3884

>T288800 WP_114834773.1 NZ_LR699115:132402-132722 [Aquicella lusitana]
MNRGEVYWIDLNPTKGSEINKQRPCVIVSATPINRARSTVVVVPLSTAARPRPPIVVEVTCLGKQVVAICDQIRTVDKSR
LLKSAGNLSAQEMDSLDESLRQVLSL

Download         Length: 321 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10012.55 Da        Isoelectric Point: 4.9543

>AT288800 WP_114834774.1 NZ_LR699115:132124-132387 [Aquicella lusitana]
MEKVLISIPDQLAARMRATIPARQRSKIITLLIEEEIEKRERALYECALAVEQDNELRREMEEWNVTLNDGLTEEGKSAL
TGKIKSK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References