Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 904277..904911 Replicon chromosome
Accession NZ_LR699114
Organism Aquicella lusitana strain SGT-39

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AQUSIP_RS04210 Protein ID WP_114835515.1
Coordinates 904507..904911 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AQUSIP_RS04205 Protein ID WP_114835516.1
Coordinates 904277..904507 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AQUSIP_RS04190 900222..901268 - 1047 WP_114835537.1 IS481 family transposase -
AQUSIP_RS04195 901350..902702 - 1353 WP_170131897.1 hypothetical protein -
AQUSIP_RS04200 903100..903930 + 831 WP_114835517.1 hypothetical protein -
AQUSIP_RS04205 904277..904507 + 231 WP_114835516.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
AQUSIP_RS04210 904507..904911 + 405 WP_114835515.1 type II toxin-antitoxin system VapC family toxin Toxin
AQUSIP_RS04215 905328..905669 + 342 WP_114835514.1 hypothetical protein -
AQUSIP_RS04220 905721..906767 - 1047 WP_114835537.1 IS481 family transposase -
AQUSIP_RS04225 906933..907910 + 978 WP_114835533.1 hypothetical protein -
AQUSIP_RS04230 907918..908369 + 452 Protein_825 recombinase family protein -
AQUSIP_RS04235 908602..909648 + 1047 WP_114835537.1 IS481 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 900222..917978 17756
- inside IScluster/Tn - - 900222..909648 9426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-127)

Antitoxin

SpoVT-AbrB domain

(7-48)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15293.70 Da        Isoelectric Point: 7.2759

>T288798 WP_114835515.1 NZ_LR699114:904507-904911 [Aquicella lusitana]
MRLRYLLDTNICIYIAKQKPATVMKKFEELEVGQVAMSVITYGELLYGANKSQSPDAAHSKLVELTTLIPALELNNEVAE
HYGDIRRNLEKFGKPIGNNDLWIASHARALDVILVTNNLREFDRVPKLRIENWV

Download         Length: 405 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9148.43 Da        Isoelectric Point: 7.2061

>AT288798 WP_114835516.1 NZ_LR699114:904277-904507 [Aquicella lusitana]
MKFAKIFKSGNSQALRLPKEFQFHTKEVEIFRRGNDVILREKPENLRHAFELLSGMPKDFFSDEREDTLPQEREFF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References