Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4010638..4011416 Replicon chromosome
Accession NZ_LR699014
Organism Citrobacter werkmanii isolate MGYG-HGUT-02535

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag FYC27_RS19520 Protein ID WP_096758632.1
Coordinates 4010638..4011126 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag FYC27_RS19525 Protein ID WP_096758633.1
Coordinates 4011123..4011416 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC27_RS19500 4005804..4006712 + 909 WP_096758628.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
FYC27_RS19505 4007295..4007612 - 318 WP_096758630.1 hypothetical protein -
FYC27_RS19510 4007743..4009206 + 1464 WP_096758631.1 hypothetical protein -
FYC27_RS19515 4010174..4010353 + 180 Protein_3773 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
FYC27_RS19520 4010638..4011126 - 489 WP_096758632.1 GNAT family N-acetyltransferase Toxin
FYC27_RS19525 4011123..4011416 - 294 WP_096758633.1 DUF1778 domain-containing protein Antitoxin
FYC27_RS19530 4012084..4015338 - 3255 WP_096758634.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3999803..4012073 12270


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17605.61 Da        Isoelectric Point: 7.7294

>T288791 WP_096758632.1 NZ_LR699014:c4011126-4010638 [Citrobacter werkmanii]
MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQLSGASRTFVCCDDVKVMAYYSLASSAVTTNTAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGLGRALMRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLVG
SV

Download         Length: 489 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10932.58 Da        Isoelectric Point: 9.8590

>AT288791 WP_096758633.1 NZ_LR699014:c4011416-4011123 [Citrobacter werkmanii]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLTRLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References