Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3872330..3872846 Replicon chromosome
Accession NZ_LR699014
Organism Citrobacter werkmanii isolate MGYG-HGUT-02535

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FYC27_RS18815 Protein ID WP_096758513.1
Coordinates 3872330..3872614 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FYC27_RS18820 Protein ID WP_096758514.1
Coordinates 3872604..3872846 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC27_RS18800 3867543..3869195 + 1653 WP_096758511.1 alpha,alpha-phosphotrehalase -
FYC27_RS18805 3869602..3871740 + 2139 WP_096758512.1 anaerobic ribonucleoside-triphosphate reductase -
FYC27_RS18810 3871862..3872326 + 465 WP_096759476.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
FYC27_RS18815 3872330..3872614 - 285 WP_096758513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FYC27_RS18820 3872604..3872846 - 243 WP_096758514.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FYC27_RS18825 3872924..3874837 - 1914 WP_096758515.1 BglG family transcription antiterminator -
FYC27_RS18830 3874859..3875599 - 741 WP_096758516.1 KDGP aldolase family protein -
FYC27_RS18835 3875596..3876714 - 1119 WP_096758517.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
FYC27_RS18840 3876698..3877831 - 1134 WP_096758518.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10815.65 Da        Isoelectric Point: 9.6730

>T288790 WP_096758513.1 NZ_LR699014:c3872614-3872330 [Citrobacter werkmanii]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSACLNGLPDCYKIKLKSSGYRLVYQVRDEVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0490

>AT288790 WP_096758514.1 NZ_LR699014:c3872846-3872604 [Citrobacter werkmanii]
MATLNVRLDDKLKNEAYAVLDKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKISLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References