Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 536565..537219 Replicon chromosome
Accession NZ_LR699014
Organism Citrobacter werkmanii isolate MGYG-HGUT-02535

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FYC27_RS02635 Protein ID WP_096755799.1
Coordinates 536812..537219 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FYC27_RS02630 Protein ID WP_096755798.1
Coordinates 536565..536831 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC27_RS02600 531779..533212 - 1434 WP_096755794.1 6-phospho-beta-glucosidase BglA -
FYC27_RS02605 533333..534061 - 729 WP_096759335.1 MurR/RpiR family transcriptional regulator -
FYC27_RS02610 534114..534425 + 312 WP_096755795.1 N(4)-acetylcytidine aminohydrolase -
FYC27_RS02615 534589..535248 + 660 WP_096755796.1 hemolysin III family protein -
FYC27_RS02620 535328..536308 - 981 WP_096755797.1 tRNA-modifying protein YgfZ -
FYC27_RS02630 536565..536831 + 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
FYC27_RS02635 536812..537219 + 408 WP_096755799.1 protein YgfX Toxin
FYC27_RS02640 537265..537786 - 522 WP_096755800.1 flavodoxin FldB -
FYC27_RS02645 537899..538795 + 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
FYC27_RS02650 538819..539532 + 714 WP_096755802.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FYC27_RS02655 539538..541271 + 1734 WP_096755803.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-131)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T288779 WP_096755799.1 NZ_LR699014:536812-537219 [Citrobacter werkmanii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT288779 WP_096755798.1 NZ_LR699014:536565-536831 [Citrobacter werkmanii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References