Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 2943968..2944475 Replicon chromosome
Accession NZ_LR699012
Organism Anaerostipes hadrus isolate MGYG-HGUT-02528

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FX119_RS14635 Protein ID WP_077327362.1
Coordinates 2943968..2944219 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FX119_RS14640 Protein ID WP_077327365.1
Coordinates 2944212..2944475 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX119_RS14615 2939067..2939270 + 204 Protein_2807 DUF3990 domain-containing protein -
FX119_RS14620 2939716..2939877 + 162 Protein_2808 phage holin family protein -
FX119_RS14625 2940355..2943521 + 3167 Protein_2809 response regulator -
FX119_RS14635 2943968..2944219 - 252 WP_077327362.1 Txe/YoeB family addiction module toxin Toxin
FX119_RS14640 2944212..2944475 - 264 WP_077327365.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FX119_RS14645 2945047..2946669 - 1623 WP_077325578.1 IS1182 family transposase -
FX119_RS14650 2946775..2949012 - 2238 WP_077327368.1 UvrD-helicase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10001.35 Da        Isoelectric Point: 9.3455

>T288777 WP_077327362.1 NZ_LR699012:c2944219-2943968 [Anaerostipes hadrus]
MNKLFTDNGWKDYVYWQTEDRKTLKKINSLINDILRNGNVGMGKPEPLTSNLSGYWSRRINDKDRLIYRIDEENIYILSC
RYH

Download         Length: 252 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10404.61 Da        Isoelectric Point: 4.3023

>AT288777 WP_077327365.1 NZ_LR699012:c2944475-2944212 [Anaerostipes hadrus]
MLAVNYTNFRENLKDYMDKATDDYETMIVTRKNNKNVVMISEESYNNLMENVYVMGNKSNYDWLMESKEQLESGKYTKHD
LIEVQDE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References