Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1334527..1335017 Replicon chromosome
Accession NZ_LR699010
Organism Lachnoanaerobaculum umeaense isolate MGYG-HGUT-02522

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FX093_RS06040 Protein ID WP_111525019.1
Coordinates 1334748..1335017 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FX093_RS06035 Protein ID WP_111525018.1
Coordinates 1334527..1334751 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX093_RS06025 1333026..1333304 + 279 WP_111525017.1 hypothetical protein -
FX093_RS06030 1333295..1334464 + 1170 Protein_1184 hypothetical protein -
FX093_RS06035 1334527..1334751 + 225 WP_111525018.1 antitoxin Antitoxin
FX093_RS06040 1334748..1335017 + 270 WP_111525019.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FX093_RS06045 1335125..1335883 - 759 Protein_1187 transposase -
FX093_RS06050 1336043..1336801 + 759 WP_111525939.1 hypothetical protein -
FX093_RS06055 1337009..1337365 + 357 WP_111525950.1 DNA-binding protein -
FX093_RS06060 1337375..1338730 + 1356 WP_111525940.1 signal recognition particle protein -
FX093_RS06065 1338828..1339070 + 243 WP_111525941.1 30S ribosomal protein S16 -
FX093_RS06070 1339083..1339310 + 228 WP_111525942.1 KH domain-containing protein -
FX093_RS06075 1339388..1339897 + 510 WP_111525943.1 ribosome maturation factor RimM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10599.25 Da        Isoelectric Point: 10.2260

>T288773 WP_111525019.1 NZ_LR699010:1334748-1335017 [Lachnoanaerobaculum umeaense]
MIYEISTTDKFDKSFKKLDRQAQRILKTWIDKNLMNCDNPRAHGKALSANRSGQWRYRVGDYRILAEIQDNRLVLILIDV
GHRKDIYLF

Download         Length: 270 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8761.96 Da        Isoelectric Point: 4.5447

>AT288773 WP_111525018.1 NZ_LR699010:1334527-1334751 [Lachnoanaerobaculum umeaense]
MSVISLRVPENELNIFKSYAKHNDKSLSEIIRITMLERIEDEYDLKAFEEYEAEKQSGTLKTRPVSELWKELDL

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References