Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1102258..1102808 Replicon chromosome
Accession NZ_LR699010
Organism Lachnoanaerobaculum umeaense isolate MGYG-HGUT-02522

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FX093_RS04995 Protein ID WP_111525534.1
Coordinates 1102527..1102808 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FX093_RS04990 Protein ID WP_111525533.1
Coordinates 1102258..1102524 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX093_RS04985 1097987..1101862 + 3876 WP_111525532.1 hypothetical protein -
FX093_RS04990 1102258..1102524 + 267 WP_111525533.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FX093_RS04995 1102527..1102808 + 282 WP_111525534.1 type II toxin-antitoxin system YafQ family toxin Toxin
FX093_RS05000 1102860..1103147 + 288 Protein_978 BREX-1 system phosphatase PglZ type A -
FX093_RS05005 1103310..1104563 + 1254 WP_111525535.1 radical SAM protein -
FX093_RS05010 1104629..1105978 + 1350 WP_111525536.1 serpin family protein -
FX093_RS05015 1106288..1106701 + 414 WP_111525537.1 hypothetical protein -
FX093_RS05020 1106881..1107147 + 267 WP_111525538.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 999500..1150023 150523


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-66)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11104.87 Da        Isoelectric Point: 8.7617

>T288772 WP_111525534.1 NZ_LR699010:1102527-1102808 [Lachnoanaerobaculum umeaense]
MKYDVQFTNQFKKDLKLAKKQRKNLDKLFEVIDILANGGTLDAKYRDYDLTGNYKGTRECHIEPNWLLIYEIYDDILVLI
LYRLGTHSELFKK

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9878.44 Da        Isoelectric Point: 4.5859

>AT288772 WP_111525533.1 NZ_LR699010:1102258-1102524 [Lachnoanaerobaculum umeaense]
MMTTNLNIRIDKDIKDQAEGIFNELGINMTTAVNIFLRTAIREHGIPFELKLDVPNEITVAAIEEGKRMMSDPLAPRYSS
MDDLKAAL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References