Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1921683..1922403 Replicon chromosome
Accession NZ_LR699009
Organism Pluralibacter gergoviae isolate MGYG-HGUT-02520

Toxin (Protein)


Gene name relE Uniprot ID A0A1Y4XQ46
Locus tag FYC31_RS09130 Protein ID WP_045287565.1
Coordinates 1922005..1922403 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FYC31_RS09125 Protein ID WP_045287566.1
Coordinates 1921683..1922012 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC31_RS09115 1918044..1919933 + 1890 WP_048253164.1 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase -
FYC31_RS09120 1920134..1921558 + 1425 WP_043086785.1 dihydrolipoyl dehydrogenase -
FYC31_RS09125 1921683..1922012 - 330 WP_045287566.1 helix-turn-helix domain-containing protein Antitoxin
FYC31_RS09130 1922005..1922403 - 399 WP_045287565.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FYC31_RS09135 1922660..1923565 - 906 WP_048253163.1 LysR family transcriptional regulator -
FYC31_RS09140 1923664..1924659 + 996 WP_048253262.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-124)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-95)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14899.16 Da        Isoelectric Point: 9.7433

>T288758 WP_045287565.1 NZ_LR699009:c1922403-1922005 [Pluralibacter gergoviae]
VRVFRTKLFNKGAKNFQLPDTALFAVAREVFEGRYEANLGGGVIKKRIAINGKGKRGGIRSIIFFKVGSHIFFADTWSKN
DTPKSGKEIDDAQLYAYRLLAETLLNLNDKQLIEMIAKNLLTEVKECEDTDE

Download         Length: 399 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12010.96 Da        Isoelectric Point: 9.6557

>AT288758 WP_045287566.1 NZ_LR699009:c1922012-1921683 [Pluralibacter gergoviae]
MSDKMTDILEFSKELNNAGILSDDKYAKINARAKACKITAQIQPLRPMSGEEIRTMRSHYGMSQTMLAATLGITTASVSK
WERDVVQPSGPALRLLNTLQLKGPDIFIA

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y4XQ46

Antitoxin

Source ID Structure

References