Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1339995..1340530 Replicon chromosome
Accession NZ_LR699009
Organism Pluralibacter gergoviae isolate MGYG-HGUT-02520

Toxin (Protein)


Gene name relE Uniprot ID A0A0J5M2C6
Locus tag FYC31_RS06395 Protein ID WP_048253968.1
Coordinates 1339995..1340282 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A089QYF2
Locus tag FYC31_RS06400 Protein ID WP_043081737.1
Coordinates 1340279..1340530 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC31_RS06380 1335585..1336271 - 687 WP_048254039.1 sel1 repeat family protein -
FYC31_RS06385 1336524..1338671 - 2148 WP_080732634.1 formate dehydrogenase subunit alpha -
FYC31_RS06390 1338969..1339904 + 936 WP_048253969.1 Rpn family recombination-promoting nuclease/putative transposase -
FYC31_RS06395 1339995..1340282 - 288 WP_048253968.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FYC31_RS06400 1340279..1340530 - 252 WP_043081737.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FYC31_RS06405 1340621..1341307 - 687 WP_043081738.1 DNA-binding transcriptional regulator CsiR -
FYC31_RS06410 1341335..1342735 - 1401 WP_048253967.1 GABA permease -
FYC31_RS06415 1342865..1344148 - 1284 WP_106912783.1 4-aminobutyrate--2-oxoglutarate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11093.04 Da        Isoelectric Point: 10.5481

>T288757 WP_048253968.1 NZ_LR699009:c1340282-1339995 [Pluralibacter gergoviae]
MSYRIKFREDALKEWNRLDKVIQQQFAKKLKKCSEDPHIPAAKLRGMPNCYKIKLRSAGFRLVYQVIDDALIVAVVAVGK
REREDVYARAGDRIR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9191.54 Da        Isoelectric Point: 4.1546

>AT288757 WP_043081737.1 NZ_LR699009:c1340530-1340279 [Pluralibacter gergoviae]
MPSIILSETTASVSELKSNPMATVSAGEGFPVAILNRNKPAFYCIPAELYERILDALDDQELVRLVNERKDQKLVDVDLD
SLL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J5M2C6

Antitoxin

Source ID Structure
AlphaFold DB A0A089QYF2

References