Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 121228..121816 Replicon chromosome
Accession NZ_LR699009
Organism Pluralibacter gergoviae isolate MGYG-HGUT-02520

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FYC31_RS00580 Protein ID WP_064360548.1
Coordinates 121228..121584 (-) Length 119 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1S2BDS7
Locus tag FYC31_RS00585 Protein ID WP_043080699.1
Coordinates 121574..121816 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC31_RS00560 116557..117336 - 780 WP_043080695.1 acetolactate decarboxylase -
FYC31_RS00565 117443..118330 + 888 WP_048254367.1 LysR family transcriptional regulator -
FYC31_RS00570 118688..120826 + 2139 WP_048254369.1 anaerobic ribonucleoside-triphosphate reductase -
FYC31_RS00575 120826..121290 + 465 WP_043080698.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
FYC31_RS00580 121228..121584 - 357 WP_064360548.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FYC31_RS00585 121574..121816 - 243 WP_043080699.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FYC31_RS00590 121895..123805 - 1911 WP_048254371.1 BglG family transcription antiterminator -
FYC31_RS00595 123823..124968 - 1146 WP_048254373.1 lactonase family protein -
FYC31_RS00600 125030..125770 - 741 WP_043080703.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13598.09 Da        Isoelectric Point: 10.8127

>T288752 WP_064360548.1 NZ_LR699009:c121584-121228 [Pluralibacter gergoviae]
MIYELVFDPRALKEWHKLGDTVRAQFKKKLAEVLCQPRQTSARLRGLPDCYKIKLKSSGYRLVYQVQDEKITVLVIAIGK
RERAAVYKDAGRRVNSLPLAQLMHNLITAPPPNQRRVL

Download         Length: 357 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8964.46 Da        Isoelectric Point: 5.1086

>AT288752 WP_043080699.1 NZ_LR699009:c121816-121574 [Pluralibacter gergoviae]
MATLNVRLDDKLKEEACTVLAKLNISPTEAVRLLFQYLAENGRMPVKTVTISDSEEALLRTVRERLADPLPGVKVRLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1S2BDS7

References