Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-KacA/DUF1778(antitoxin)
Location 2294962..2295756 Replicon chromosome
Accession NZ_LR699008
Organism Hafnia alvei isolate MGYG-HGUT-02508

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag FYB81_RS10670 Protein ID WP_096387615.1
Coordinates 2295235..2295756 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID A0A097R2F1
Locus tag FYB81_RS10665 Protein ID WP_025801385.1
Coordinates 2294962..2295231 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYB81_RS10650 2290560..2291591 - 1032 WP_043493238.1 Mal regulon transcriptional regulator MalI -
FYB81_RS10655 2291842..2293437 + 1596 WP_111329514.1 maltose/glucose-specific PTS transporter subunit IIBC -
FYB81_RS10660 2293521..2294696 + 1176 WP_025801384.1 pyridoxal phosphate-dependent aminotransferase -
FYB81_RS10665 2294962..2295231 + 270 WP_025801385.1 DUF1778 domain-containing protein Antitoxin
FYB81_RS10670 2295235..2295756 + 522 WP_096387615.1 GNAT family N-acetyltransferase Toxin
FYB81_RS10675 2295954..2296952 + 999 WP_103009725.1 adenosine deaminase -
FYB81_RS10680 2297550..2298545 - 996 WP_111329516.1 bile acid:sodium symporter -
FYB81_RS10685 2298707..2299750 - 1044 WP_111329518.1 oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(92-152)

Antitoxin

Vibrio phage ICP1, Orf50

(3-88)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19412.24 Da        Isoelectric Point: 6.9676

>T288744 WP_096387615.1 NZ_LR699008:2295235-2295756 [Hafnia alvei]
MPDLTIAIFSSEAEYDFSDFDCGEESLNVFLTDHLARQHNARILRGYLLITQTLKPKVVGYYTLSGSCFEKETLPSNTQK
RKVPYVNVPSITLGRLAIQKDLHGQEWGTALVTHAMQVVYRASLAVGVHGMFVDALNEKAKQFYLKLGFIALTGNNANSL
FYPTKSIEKLFED

Download         Length: 522 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10097.51 Da        Isoelectric Point: 5.8580

>AT288744 WP_025801385.1 NZ_LR699008:2294962-2295231 [Hafnia alvei]
MSALKKQRIDLRLTDEDKNAIEEAAAMSNQTITQFMLTSASERAAEVIEQHRRLILSDESWNLVMDAISTPPAPNDRLKR
AAKRLQSME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A097R2F1

References