Detailed information of TA system TA288738

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeUV (cbtA-cbeA)/CbtA-CbeA
• Location: 416813..417531
• Replicon: chromosome
• Accession: NZ_LR699007
• Organism: Morganella morganii isolate MGYG-HGUT-02512

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: FX120_RS02030
• Protein ID: WP_111759529.1
• Coordinates: 417211..417531 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yeeU
• Uniprot ID: -
• Locus tag: FX120_RS02025
• Protein ID: WP_111759528.1
• Coordinates: 416813..417169 (+)
• Length: 119 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FX120_RS01990	413168..413602	+	435	WP_111759521.1	hypothetical protein	-
FX120_RS01995	413622..414425	+	804	WP_111759522.1	hypothetical protein	-
FX120_RS02005	414642..415076	+	435	WP_111759524.1	hypothetical protein	-
FX120_RS02010	415190..416011	+	822	WP_111759525.1	DUF945 domain-containing protein	-
FX120_RS02015	416081..416551	+	471	WP_111759526.1	DNA repair protein RadC	-
FX120_RS02020	416560..416781	+	222	WP_111759527.1	DUF987 family protein	-
FX120_RS02025	416813..417169	+	357	WP_111759528.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
FX120_RS02030	417211..417531	+	321	WP_111759529.1	TA system toxin CbtA family protein	Toxin
FX120_RS02035	417645..418481	+	837	WP_111759530.1	DUF4942 domain-containing protein	-
FX120_RS02040	418873..420147	+	1275	WP_004234643.1	integrase arm-type DNA-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	390864..433818	42954

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (12-105)

Antitoxin

• Antitoxin CbeA (18-117)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12096.84 Da
• Isoelectric Point: 6.0590

>T288738 WP_111759529.1 NZ_LR699007:417211-417531 [Morganella morganii]
MHISTVPVTVPVSSRLSPVQVWQQLLTYLLEHYYGLTLNDTPFHDDSAIQEHIEAGITLADAVNFLVERYELIRTDRKGF
TWQGQTPFLTAIDILRARRATGLMNI

Nucleotide

• Length: 321 bp

Antitoxin

Protein

• Length: 119 a.a.
• Molecular weight: 13018.60 Da
• Isoelectric Point: 6.0607

>AT288738 WP_111759528.1 NZ_LR699007:416813-417169 [Morganella morganii]
MQSTTLSGTSAENATCLQWGLKRNITPCFGARLVQEGNRLYFLADRAGFNGSFSDDEALRLDQAFPLIMKQLERMLTTGE
LDPRSQHSVALHHNGLTSEADTLGSHGYVYIAIYPSQP

Nucleotide

• Length: 357 bp