Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1261762..1262367 Replicon chromosome
Accession NZ_LR698998
Organism Paenibacillus odorifer isolate MGYG-HGUT-02414

Toxin (Protein)


Gene name mazF Uniprot ID A0A1R0YSQ6
Locus tag FYB94_RS05470 Protein ID WP_036686777.1
Coordinates 1262017..1262367 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FYB94_RS05465 Protein ID WP_154117276.1
Coordinates 1261762..1262013 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYB94_RS05445 1257147..1258532 + 1386 WP_111502784.1 helix-turn-helix transcriptional regulator -
FYB94_RS05450 1258681..1258854 + 174 WP_111502786.1 aspartyl-phosphate phosphatase Spo0E family protein -
FYB94_RS05455 1259061..1260146 + 1086 WP_076137665.1 outer membrane lipoprotein carrier protein LolA -
FYB94_RS05460 1260335..1261516 + 1182 WP_076137663.1 alanine racemase -
FYB94_RS05465 1261762..1262013 + 252 WP_154117276.1 ribbon-helix-helix protein, CopG family Antitoxin
FYB94_RS05470 1262017..1262367 + 351 WP_036686777.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FYB94_RS05475 1262576..1263133 + 558 WP_172628782.1 TetR family transcriptional regulator -
FYB94_RS05480 1263305..1264504 + 1200 WP_076137661.1 MFS transporter -
FYB94_RS05485 1264744..1266906 + 2163 WP_179088937.1 RNA-binding transcriptional accessory protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(2-35)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12778.71 Da        Isoelectric Point: 5.1284

>T288719 WP_036686777.1 NZ_LR698998:1262017-1262367 [Paenibacillus odorifer]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAAAHGFDRDSVILLEQV
RTIDKQRLTDKITHLDDETMKKVDESLQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9487.94 Da        Isoelectric Point: 5.1184

>AT288719 WP_154117276.1 NZ_LR698998:1261762-1262013 [Paenibacillus odorifer]
MISLPDHLLQEVDGIVQLENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLV
SGV

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1R0YSQ6

Antitoxin

Source ID Structure

References