Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 302451..303022 Replicon chromosome
Accession NZ_LR698990
Organism Bifidobacterium adolescentis isolate MGYG-HGUT-02395

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FX023_RS01180 Protein ID WP_003807675.1
Coordinates 302451..302750 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0C2Z6P7
Locus tag FX023_RS01185 Protein ID WP_034984155.1
Coordinates 302750..303022 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX023_RS01170 299116..299844 + 729 WP_003807670.1 type 1 glutamine amidotransferase -
FX023_RS01175 300156..302354 + 2199 WP_039774710.1 ABC-F family ATP-binding cassette domain-containing protein -
FX023_RS01180 302451..302750 - 300 WP_003807675.1 type II toxin-antitoxin system YafQ family toxin Toxin
FX023_RS01185 302750..303022 - 273 WP_034984155.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FX023_RS01190 303136..303972 - 837 WP_039774711.1 hypothetical protein -
FX023_RS01195 304156..304695 + 540 WP_003807679.1 hypothetical protein -
FX023_RS01200 304688..305206 + 519 WP_130082043.1 hypothetical protein -
FX023_RS01205 305265..306419 - 1155 WP_046998989.1 ATP-binding protein -
FX023_RS01210 306422..307051 - 630 WP_039774712.1 response regulator transcription factor -
FX023_RS01215 307188..307829 + 642 WP_039774713.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-98)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11662.09 Da        Isoelectric Point: 8.0955

>T288718 WP_003807675.1 NZ_LR698990:c302750-302451 [Bifidobacterium adolescentis]
MGRLTADFAKAFSRDLKKNAKRRNWNLTELEKVIDLVVENTPETLEELRRRHNMHTLSGNWRGRYECHVANAGDWLVIWS
SNDSVAFFERTGSHDELFR

Download         Length: 300 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9714.91 Da        Isoelectric Point: 4.5535

>AT288718 WP_034984155.1 NZ_LR698990:c303022-302750 [Bifidobacterium adolescentis]
MSASTLTIRMDDELKRSAADVAEYYGLDLSSVVRAVFKQMVNTGRIPLTFAPEEPNGESLNAAAEADSFMASGKTGRFTN
GHDLLEAAMR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0C2Z6P7

References