Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3381768..3383469 Replicon chromosome
Accession NZ_LR698987
Organism Leminorella richardii isolate MGYG-HGUT-02385

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag FX055_RS15390 Protein ID WP_111741510.1
Coordinates 3382537..3383469 (+) Length 311 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag FX055_RS15385 Protein ID WP_172622636.1
Coordinates 3381768..3382550 (+) Length 261 a.a.

Genomic Context

FX055_RS15360FX055_RS15370FX055_RS15385FX055_RS15390FX055_RS15365FX055_RS15380FX055_RS15395FX055_RS15400FX055_RS15405FX055_RS15410
Location: 3377092..3378123 (1032 bp)
Type: Others
Protein ID: WP_170126559.1
Location: 3379344..3380231 (888 bp)
Type: Others
Protein ID: WP_111741508.1
Location: 3381768..3382550 (783 bp)
Type: Antitoxin
Protein ID: WP_172622636.1
Location: 3382537..3383469 (933 bp)
Type: Toxin
Protein ID: WP_111741510.1
Location: 3378200..3379066 (867 bp)
Type: Others
Protein ID: WP_111741507.1
Location: 3380743..3381210 (468 bp)
Type: Others
Protein ID: WP_111741509.1
Location: 3384129..3385160 (1032 bp)
Type: Others
Protein ID: WP_111741511.1
Location: 3385157..3386107 (951 bp)
Type: Others
Protein ID: WP_111741512.1
Location: 3386104..3386901 (798 bp)
Type: Others
Protein ID: WP_111741513.1
Location: 3386916..3387785 (870 bp)
Type: Others
Protein ID: WP_111741514.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FX055_RS153603377092..3378123+1032WP_170126559.1DUF1176 domain-containing protein-
FX055_RS153653378200..3379066-867WP_111741507.1LysR family transcriptional regulator-
FX055_RS153703379344..3380231+888WP_111741508.1class A beta-lactamase-
FX055_RS153803380743..3381210-468WP_111741509.1hypothetical protein-
FX055_RS153853381768..3382550+783WP_172622636.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing proteinAntitoxin
FX055_RS153903382537..3383469+933WP_111741510.1nucleotidyl transferase AbiEii/AbiGii toxin family proteinToxin
FX055_RS153953384129..3385160-1032WP_111741511.14-hydroxy-2-oxovalerate aldolase-
FX055_RS154003385157..3386107-951WP_111741512.1acetaldehyde dehydrogenase (acetylating)-
FX055_RS154053386104..3386901-798WP_111741513.12-keto-4-pentenoate hydratase-
FX055_RS154103386916..3387785-870WP_111741514.1alpha/beta fold hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-278)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(3-90)


Sequences

Toxin        


Download         Length: 311 a.a.        Molecular weight: 35069.49 Da        Isoelectric Point: 7.7368

>T288715 WP_111741510.1 NZ_LR698987:3382537-3383469 [Leminorella richardii]
MDLRDSYARQVRLLMAALPHVAKESCFALKGGTAINLFVQDFPRLSVDIDLAYKTFADRDTDLAAINDALKRITASLNSK
PGITAIRQENKADEKRIIVNTTDAQIKIEVSPVWRGLLLPPTEMPVCEQVEMEYGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLKKPGLTREIFDGFLCYLAGHPRPIAELLTPNWDTARIATLYAQEFSGMTTQRETSLESLLSVTTLLPQA
LKSHLTDRDRQFLLSYKQNTPDWSLYRYPEIQHLPAIRWKLRNLAVLKEKNPAKNTAAVSKLEGVLEQYF

Download         Length: 933 bp

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29329.62 Da        Isoelectric Point: 8.1223

>AT288715 WP_172622636.1 NZ_LR698987:3381768-3382550 [Leminorella richardii]
MPNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYLYVQNGWLRRIAHGVYCRTGRDPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGHAHYTEPGRQQIWLALPAYVKLPGWFATFEQSATFVTLYTSGLTVDITLLTTELKIGDRQLAGSVPELAAYEIA
CGVPSLISFEHADALFQGMNLLSPRKLQTLLCASHSVKTNRVMLYLARRNEHPYFRYLDQSGIETGTGKRQIVPGGWLEP
DYQITVPRAFKPEGVEDGSA

Download         Length: 783 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References