Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 565588..566077 Replicon chromosome
Accession NZ_LR698979
Organism Bifidobacterium thermophilum isolate MGYG-HGUT-02334

Toxin (Protein)


Gene name pasB Uniprot ID M4RB99
Locus tag FXZ37_RS02055 Protein ID WP_015449982.1
Coordinates 565808..566077 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID M4REW7
Locus tag FXZ37_RS02050 Protein ID WP_015449981.1
Coordinates 565588..565824 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXZ37_RS02045 564226..565308 + 1083 WP_044282335.1 hypothetical protein -
FXZ37_RS02050 565588..565824 + 237 WP_015449981.1 ribbon-helix-helix domain-containing protein Antitoxin
FXZ37_RS02055 565808..566077 + 270 WP_015449982.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXZ37_RS02060 566345..566986 - 642 WP_081602282.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
FXZ37_RS02065 567004..567908 + 905 Protein_402 A/G-specific adenine glycosylase -
FXZ37_RS02070 567977..568558 + 582 WP_052307709.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 558375..566944 8569


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10358.21 Da        Isoelectric Point: 10.4616

>T288699 WP_015449982.1 NZ_LR698979:565808-566077 [Bifidobacterium thermophilum]
MAWKIEIDKGVQRSMKKLDRHVAKRIIAKLREISQLEDPRSTGKALVGNLAGLWRYRVGDYQIVCDIEDEVLLILVVDVA
HRSKVYKRR

Download         Length: 270 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8876.10 Da        Isoelectric Point: 4.2821

>AT288699 WP_015449981.1 NZ_LR698979:565588-565824 [Bifidobacterium thermophilum]
MATATAALRMPVELAARYDRLAKATGRTKTFYMNEALTESIDRLEYEYGIMKKVEDWRAGILETVTLDELEESLGLED

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M4RB99

Antitoxin

Source ID Structure
AlphaFold DB M4REW7

References