288696

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 2892012..2892651 Replicon chromosome
Accession NZ_LR698965
Organism Planococcus massiliensis isolate MGYG-HGUT-01482

Toxin (Protein)


Gene name pemK Uniprot ID A0A098ENU8
Locus tag FXZ10_RS14505 Protein ID WP_052653123.1
Coordinates 2892012..2892362 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag FXZ10_RS14510 Protein ID WP_110925660.1
Coordinates 2892367..2892651 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXZ10_RS14470 2887555..2888337 - 783 WP_052653111.1 RNA polymerase sigma factor SigB -
FXZ10_RS14475 2888315..2888785 - 471 WP_052653113.1 anti-sigma B factor RsbW -
FXZ10_RS14480 2888787..2889116 - 330 WP_052653115.1 anti-sigma factor antagonist -
FXZ10_RS14485 2889210..2890211 - 1002 WP_052653117.1 PP2C family protein-serine/threonine phosphatase -
FXZ10_RS14490 2890224..2890625 - 402 WP_052653119.1 anti-sigma regulatory factor -
FXZ10_RS14495 2890628..2890990 - 363 WP_036807366.1 STAS domain-containing protein -
FXZ10_RS14500 2890987..2891817 - 831 WP_052653121.1 STAS domain-containing protein -
FXZ10_RS14505 2892012..2892362 - 351 WP_052653123.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FXZ10_RS14510 2892367..2892651 - 285 WP_110925660.1 transcriptional regulator Antitoxin
FXZ10_RS14515 2892749..2893849 - 1101 WP_052653127.1 alanine racemase -
FXZ10_RS14520 2893868..2894218 - 351 WP_052653129.1 holo-ACP synthase -
FXZ10_RS14525 2894285..2894893 + 609 WP_052653131.1 rhomboid family intramembrane serine protease -
FXZ10_RS14530 2894896..2896455 - 1560 WP_052654653.1 PH domain-containing protein -
FXZ10_RS14535 2896448..2896927 - 480 WP_052653133.1 PH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12895.00 Da        Isoelectric Point: 5.8882

>T288696 WP_052653123.1 NZ_LR698965:c2892362-2892012 [Planococcus massiliensis]
MIVKRGDVFFAELSPVVGSEQGGTRPVLVIQNDIGNRFSPTVIIAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQL
RTIDKSRLTDKITQLDETLMEKVDEALEISVGLVKF

Download         Length: 351 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10674.07 Da        Isoelectric Point: 6.6351

>AT288696 WP_110925660.1 NZ_LR698965:c2892651-2892367 [Planococcus massiliensis]
VYGKSKTKEVVVKLPKQMISELTAHSDEQIQERGDYVYVSTQRVTKNIYDSHHIREAMIKGYVEMSQINLSIACECSHAE
YEAEHTTVRLVSGG

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A098ENU8

Antitoxin

Source ID Structure

References