Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/PIN-RelB
Location 1984534..1985387 Replicon chromosome
Accession NZ_LR655210
Organism Bifidobacterium longum subsp. infantis isolate B.longum_ssp_infantis_6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BILO16373828_RS09730 Protein ID WP_014484735.1
Coordinates 1984534..1985025 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B7GQF3
Locus tag BILO16373828_RS09735 Protein ID WP_012577299.1
Coordinates 1985025..1985387 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BILO16373828_RS09705 1980387..1981289 - 903 WP_014484737.1 Bax inhibitor-1/YccA family protein -
BILO16373828_RS09710 1981286..1981504 - 219 WP_014484736.1 hypothetical protein -
BILO16373828_RS09715 1981458..1981598 + 141 Protein_1806 DNA-binding response regulator -
BILO16373828_RS09720 1981639..1982280 + 642 WP_013140893.1 GNAT family N-acetyltransferase -
BILO16373828_RS09725 1982369..1984474 + 2106 WP_012577301.1 DUF262 domain-containing protein -
BILO16373828_RS09730 1984534..1985025 - 492 WP_014484735.1 PIN domain-containing protein Toxin
BILO16373828_RS09735 1985025..1985387 - 363 WP_012577299.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BILO16373828_RS09740 1985533..1988232 - 2700 WP_012577298.1 aconitate hydratase AcnA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-141)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-53)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18398.02 Da        Isoelectric Point: 4.5590

>T288656 WP_014484735.1 NZ_LR655210:c1985025-1984534 [Bifidobacterium longum subsp. infantis]
MTDVSMQRILLDTNVLLDYLLHRDDHAKMAEAVMELGAKNNVTLLCASLSLKDIAYLLSSAIRREFKPNESEVENFTRNF
LSSRVPWRCIEQVKEMCDIVAVDESTCDKAFSLQKRHRDFEDDLIIVAAQQSGANCVVTSDAELISHFPEYCKTPAEIVA
ALE

Download         Length: 492 bp

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 14034.08 Da        Isoelectric Point: 5.0733

>AT288656 WP_012577299.1 NZ_LR655210:c1985387-1985025 [Bifidobacterium longum subsp. infantis]
MTMVQMNVRIDAKLKNEVEEVLKGKGVSVSDVIRSLWLYIADRKEVPALETTAEEQAREEEKQRKLKLIREGTGYVHKEL
VKAGLISEDTDLMEGLTYKQFRDKMYDEQLDTYYNMKRAD

Download         Length: 363 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB B7GQF3

References