Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1244999..1245565 Replicon chromosome
Accession NZ_LR655209
Organism Bifidobacterium breve isolate B.breve_1_mod

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BWLFYP14_RS05615 Protein ID WP_144181702.1
Coordinates 1245272..1245565 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BWLFYP14_RS05610 Protein ID WP_101674005.1
Coordinates 1244999..1245268 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWLFYP14_RS05580 1240955..1241968 - 1014 WP_172618571.1 VanZ family protein -
BWLFYP14_RS05585 1242115..1242940 + 826 Protein_1032 aminotransferase class V-fold PLP-dependent enzyme -
BWLFYP14_RS05590 1243126..1243260 + 135 WP_101674002.1 DUF2316 family protein -
BWLFYP14_RS05595 1243301..1243834 - 534 WP_101674003.1 GNAT family N-acetyltransferase -
BWLFYP14_RS05600 1244189..1244308 + 120 WP_171843146.1 IS3 family transposase -
BWLFYP14_RS05605 1244317..1244814 + 498 Protein_1036 FtsX-like permease family protein -
BWLFYP14_RS05610 1244999..1245268 + 270 WP_101674005.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BWLFYP14_RS05615 1245272..1245565 + 294 WP_144181702.1 type II toxin-antitoxin system YafQ family toxin Toxin
BWLFYP14_RS05620 1245776..1245972 + 197 Protein_1039 permease -
BWLFYP14_RS05625 1246296..1247876 + 1581 WP_144181703.1 amino acid permease -
BWLFYP14_RS05630 1248118..1248357 - 240 WP_014483708.1 hypothetical protein -
BWLFYP14_RS05635 1248655..1249008 + 354 WP_014483707.1 DUF488 domain-containing protein -
BWLFYP14_RS10605 1249074..1249502 - 429 WP_065470715.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-94)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-87)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11190.93 Da        Isoelectric Point: 9.7881

>T288650 WP_144181702.1 NZ_LR655209:1245272-1245565 [Bifidobacterium breve]
MLKPDYTAAFQRDIKKLKRKHADLRPLKEVIRLVLEDTADSKEALRRRHRTHTLTGDLNGVLECHIGNAGDWLLLWIRDD
GTAMFMRTGSHDELLGK

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9860.16 Da        Isoelectric Point: 4.5742

>AT288650 WP_101674005.1 NZ_LR655209:1244999-1245268 [Bifidobacterium breve]
VSMASVTVRVDADTKQKAANIAEDLGLDLSSVTRAFYKQIVREKRIPLNLSYTTVPPETMEALDEAKNRLVDGQPRFNSA
DEMFDSLGI

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References