Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | BrnTA/BrnT_toxin-BrnA |
Location | 535107..535644 | Replicon | chromosome |
Accession | NZ_LR595899 | ||
Organism | Burkholderia pseudomallei isolate UKMR15 |
Toxin (Protein)
Gene name | brnT | Uniprot ID | Q2T6G2 |
Locus tag | HU776_RS20525 | Protein ID | WP_004549731.1 |
Coordinates | 535107..535376 (+) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | brnA | Uniprot ID | Q63NA3 |
Locus tag | HU776_RS20530 | Protein ID | WP_004525420.1 |
Coordinates | 535360..535644 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HU776_RS20490 | 530851..531891 | - | 1041 | WP_197970191.1 | ImmA/IrrE family metallo-endopeptidase | - |
HU776_RS20495 | 532107..532391 | - | 285 | WP_009961460.1 | type II toxin-antitoxin system HigB family toxin | - |
HU776_RS20500 | 533295..533537 | - | 243 | WP_009961458.1 | hypothetical protein | - |
HU776_RS20505 | 533585..533743 | - | 159 | WP_004549802.1 | hypothetical protein | - |
HU776_RS20510 | 533740..533982 | - | 243 | WP_004545584.1 | hypothetical protein | - |
HU776_RS20515 | 534120..534251 | - | 132 | WP_009923452.1 | bacteriophage protein Gp48 | - |
HU776_RS20520 | 534261..534536 | - | 276 | WP_025988352.1 | hypothetical protein | - |
HU776_RS20525 | 535107..535376 | + | 270 | WP_004549731.1 | BrnT family toxin | Toxin |
HU776_RS20530 | 535360..535644 | + | 285 | WP_004525420.1 | BrnA antitoxin family protein | Antitoxin |
HU776_RS20535 | 536291..536674 | + | 384 | Protein_440 | DDE-type integrase/transposase/recombinase | - |
HU776_RS20540 | 536637..537065 | + | 429 | Protein_441 | IS110 family transposase | - |
HU776_RS20545 | 537292..537408 | - | 117 | Protein_442 | IS3 family transposase | - |
HU776_RS20550 | 537674..539134 | + | 1461 | WP_004547073.1 | metallophosphoesterase | - |
HU776_RS20555 | 539293..540555 | + | 1263 | WP_004537187.1 | c-type cytochrome | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q2T6G2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0F6L9S8 |