Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 570646..571264 Replicon chromosome
Accession NZ_LR595857
Organism Streptococcus sp. NCTC 11567 strain NCTC11567

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FQT67_RS03055 Protein ID WP_003058081.1
Coordinates 570646..570987 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FQT67_RS03060 Protein ID WP_003058067.1
Coordinates 570977..571264 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQT67_RS03035 566109..567353 - 1245 WP_014612120.1 site-specific integrase -
FQT67_RS03040 567364..567561 - 198 WP_003058094.1 transposase -
FQT67_RS03045 567581..568684 - 1104 WP_046177356.1 CHAP domain-containing protein -
FQT67_RS03050 568687..570588 - 1902 WP_003058051.1 hypothetical protein -
FQT67_RS03055 570646..570987 - 342 WP_003058081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FQT67_RS03060 570977..571264 - 288 WP_003058067.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FQT67_RS03065 571335..573833 - 2499 WP_003058044.1 ATP-binding protein -
FQT67_RS03070 573817..574233 - 417 WP_003058056.1 conjugal transfer protein -
FQT67_RS03075 574242..574460 - 219 WP_003058071.1 hypothetical protein -
FQT67_RS03080 574457..575398 - 942 WP_003058075.1 conjugal transfer protein -
FQT67_RS03085 575411..575674 - 264 WP_003058063.1 hypothetical protein -
FQT67_RS03090 575684..575956 - 273 WP_046177355.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 566109..593452 27343


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T288639 WP_003058081.1 NZ_LR595857:c570987-570646 [Streptococcus sp. NCTC 11567]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10869.33 Da        Isoelectric Point: 4.3885

>AT288639 WP_003058067.1 NZ_LR595857:c571264-570977 [Streptococcus sp. NCTC 11567]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKDLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References