Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 570646..571264 Replicon chromosome
Accession NZ_LR595857
Organism Streptococcus sp. NCTC 11567 strain NCTC11567

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FQT67_RS03055 Protein ID WP_003058081.1
Coordinates 570646..570987 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FQT67_RS03060 Protein ID WP_003058067.1
Coordinates 570977..571264 (-) Length 96 a.a.

Genomic Context

FQT67_RS03035FQT67_RS03040FQT67_RS03045FQT67_RS03050FQT67_RS03055FQT67_RS03060FQT67_RS03065FQT67_RS03070FQT67_RS03075FQT67_RS03080FQT67_RS03085FQT67_RS03090
Location: 566109..567353 (1245 bp)
Type: Others
Protein ID: WP_014612120.1
Location: 567364..567561 (198 bp)
Type: Others
Protein ID: WP_003058094.1
Location: 567581..568684 (1104 bp)
Type: Others
Protein ID: WP_046177356.1
Location: 568687..570588 (1902 bp)
Type: Others
Protein ID: WP_003058051.1
Location: 570646..570987 (342 bp)
Type: Toxin
Protein ID: WP_003058081.1
Location: 570977..571264 (288 bp)
Type: Antitoxin
Protein ID: WP_003058067.1
Location: 571335..573833 (2499 bp)
Type: Others
Protein ID: WP_003058044.1
Location: 573817..574233 (417 bp)
Type: Others
Protein ID: WP_003058056.1
Location: 574242..574460 (219 bp)
Type: Others
Protein ID: WP_003058071.1
Location: 574457..575398 (942 bp)
Type: Others
Protein ID: WP_003058075.1
Location: 575411..575674 (264 bp)
Type: Others
Protein ID: WP_003058063.1
Location: 575684..575956 (273 bp)
Type: Others
Protein ID: WP_046177355.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FQT67_RS03035566109..567353-1245WP_014612120.1site-specific integrase-
FQT67_RS03040567364..567561-198WP_003058094.1transposase-
FQT67_RS03045567581..568684-1104WP_046177356.1CHAP domain-containing protein-
FQT67_RS03050568687..570588-1902WP_003058051.1hypothetical protein-
FQT67_RS03055570646..570987-342WP_003058081.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FQT67_RS03060570977..571264-288WP_003058067.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
FQT67_RS03065571335..573833-2499WP_003058044.1ATP-binding protein-
FQT67_RS03070573817..574233-417WP_003058056.1conjugal transfer protein-
FQT67_RS03075574242..574460-219WP_003058071.1hypothetical protein-
FQT67_RS03080574457..575398-942WP_003058075.1conjugal transfer protein-
FQT67_RS03085575411..575674-264WP_003058063.1hypothetical protein-
FQT67_RS03090575684..575956-273WP_046177355.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--566109..59345227343


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T288639 WP_003058081.1 NZ_LR595857:c570987-570646 [Streptococcus sp. NCTC 11567]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10869.33 Da        Isoelectric Point: 4.3885

>AT288639 WP_003058067.1 NZ_LR595857:c571264-570977 [Streptococcus sp. NCTC 11567]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKDLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References