Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 835187..835844 Replicon chromosome
Accession NZ_LR595855
Organism Raoultella terrigena strain NCTC9189

Toxin (Protein)


Gene name cptA Uniprot ID A0A4V6J1V0
Locus tag FQU09_RS04075 Protein ID WP_041147144.1
Coordinates 835434..835844 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FQU09_RS04070 Protein ID WP_041147145.1
Coordinates 835187..835453 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQU09_RS04045 830267..831700 - 1434 WP_041147149.1 6-phospho-beta-glucosidase -
FQU09_RS04050 831821..832549 - 729 WP_045857150.1 MurR/RpiR family transcriptional regulator -
FQU09_RS04055 832599..832910 + 312 WP_143966477.1 N(4)-acetylcytidine aminohydrolase -
FQU09_RS04060 833070..833729 + 660 WP_041147747.1 hemolysin III family protein -
FQU09_RS04065 833835..834818 - 984 WP_143966478.1 tRNA-modifying protein YgfZ -
FQU09_RS04070 835187..835453 + 267 WP_041147145.1 FAD assembly factor SdhE Antitoxin
FQU09_RS04075 835434..835844 + 411 WP_041147144.1 protein YgfX Toxin
FQU09_RS04080 835893..836414 - 522 WP_041147143.1 flavodoxin FldB -
FQU09_RS04085 836573..837469 + 897 WP_041147142.1 site-specific tyrosine recombinase XerD -
FQU09_RS04090 837493..838206 + 714 WP_076948124.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FQU09_RS04095 838212..839945 + 1734 WP_143966479.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16133.03 Da        Isoelectric Point: 11.3523

>T288627 WP_041147144.1 NZ_LR595855:835434-835844 [Raoultella terrigena]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACQGEIKLMTDSRLRWQKA
EWEIVGMPWVINSGMLLRLRHPQTRRSQHLWVAADSMDAKEWRDLRRLVLNKPAQD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10554.07 Da        Isoelectric Point: 4.8432

>AT288627 WP_041147145.1 NZ_LR595855:835187-835453 [Raoultella terrigena]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKLLFIRLLENDDPDLFNWLMNHGEPSDAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V6J1V0

Antitoxin

Source ID Structure

References