Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 5419755..5420322 Replicon chromosome
Accession NZ_LR594689
Organism Variovorax sp. WDL1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E5P1_RS26230 Protein ID WP_068678114.1
Coordinates 5419755..5420126 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E5P1_RS26235 Protein ID WP_083944382.1
Coordinates 5420113..5420322 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5P1_RS26200 5414842..5415699 + 858 WP_068675210.1 chemotaxis protein CheR -
E5P1_RS26205 5416616..5417227 + 612 WP_068678107.1 chemoreceptor glutamine deamidase CheD -
E5P1_RS26210 5417224..5418300 + 1077 WP_068678106.1 chemotaxis response regulator protein-glutamate methylesterase -
E5P1_RS26215 5418340..5418738 + 399 WP_068678105.1 chemotaxis response regulator CheY -
E5P1_RS26220 5418740..5419378 + 639 WP_068678104.1 protein phosphatase CheZ -
E5P1_RS26225 5419496..5419723 + 228 WP_068678103.1 hypothetical protein -
E5P1_RS26230 5419755..5420126 - 372 WP_068678114.1 type II toxin-antitoxin system VapC family toxin Toxin
E5P1_RS26235 5420113..5420322 - 210 WP_083944382.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
E5P1_RS26240 5420515..5421657 + 1143 WP_068678102.1 flagellar type III secretion system protein FlhB -
E5P1_RS26245 5421654..5423750 + 2097 WP_068678101.1 flagellar biosynthesis protein FlhA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-46)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13564.77 Da        Isoelectric Point: 6.3280

>T288590 WP_068678114.1 NZ_LR594689:c5420126-5419755 [Variovorax sp. WDL1]
MILVDTSVWIDHLARGDSGLQSLLEEGEVLMHPYIVAEIALGSLTRRDETVGALQALPEVTVARHVEVMAFLGNERLFGI
GIGYVDLHLLAATRLAAGTKLWTRDRRLLQAALRLDLARFPAH

Download         Length: 372 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7536.65 Da        Isoelectric Point: 12.0931

>AT288590 WP_083944382.1 NZ_LR594689:c5420322-5420113 [Variovorax sp. WDL1]
MRTTVTLDDELLSQARAFTGIQENSALLQQALKALVQREAARRLARLGGSAPGLRPAPRRRGKVADDPR

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References