Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1984533..1985100 Replicon chromosome
Accession NZ_LR594675
Organism Variovorax sp. PBS-H4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E5CHR_RS09520 Protein ID WP_162579453.1
Coordinates 1984533..1984904 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E5CHR_RS09525 Protein ID WP_162579454.1
Coordinates 1984891..1985100 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5CHR_RS09495 1980775..1981632 + 858 WP_162579449.1 chemotaxis protein CheR -
E5CHR_RS09500 1981739..1982350 + 612 WP_162579450.1 chemoreceptor glutamine deamidase CheD -
E5CHR_RS09505 1982347..1983426 + 1080 WP_174255710.1 chemotaxis response regulator protein-glutamate methylesterase -
E5CHR_RS09510 1983454..1983852 + 399 WP_162579451.1 chemotaxis response regulator CheY -
E5CHR_RS09515 1983854..1984492 + 639 WP_162579452.1 protein phosphatase CheZ -
E5CHR_RS09520 1984533..1984904 - 372 WP_162579453.1 PIN domain nuclease Toxin
E5CHR_RS09525 1984891..1985100 - 210 WP_162579454.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
E5CHR_RS09530 1985291..1986436 + 1146 WP_162579455.1 flagellar type III secretion system protein FlhB -
E5CHR_RS09535 1986433..1988529 + 2097 WP_162579456.1 flagellar biosynthesis protein FlhA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-46)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13596.86 Da        Isoelectric Point: 6.9899

>T288582 WP_162579453.1 NZ_LR594675:c1984904-1984533 [Variovorax sp. PBS-H4]
MILVDTSVWIDHLARGDSRLQSLLEEGEVLMHPYIVAEIALGSLTRRKETVGALQALPEIPAARHDEVMAFLGNERLFGL
GIGYVDLHLLAATRLAVGTKLWTRDRRLLQAALKFNLAAFAAH

Download         Length: 372 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7499.55 Da        Isoelectric Point: 12.1496

>AT288582 WP_162579454.1 NZ_LR594675:c1985100-1984891 [Variovorax sp. PBS-H4]
MRTTVTLDDELLSQARTFTGIQENSALIQQALKTLVQREAARRLARLGGSAPGLQAAPRRRGKGANDPR

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References