288578

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 488516..489090 Replicon plasmid 3
Accession NZ_LR594668
Organism Variovorax sp. SRS16

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag E5P2_RS34570 Protein ID WP_162571554.1
Coordinates 488516..488812 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag E5P2_RS34575 Protein ID WP_162571555.1
Coordinates 488800..489090 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5P2_RS34545 484511..485749 + 1239 WP_162571549.1 DUF4942 domain-containing protein -
E5P2_RS34550 485866..486147 + 282 WP_162571550.1 hypothetical protein -
E5P2_RS34555 486287..486595 + 309 WP_162571551.1 transcriptional regulator -
E5P2_RS34560 486711..487748 + 1038 WP_162571552.1 ParB/RepB/Spo0J family partition protein -
E5P2_RS34565 487955..488332 + 378 WP_162571553.1 conjugal transfer protein TraO -
E5P2_RS34570 488516..488812 - 297 WP_162571554.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E5P2_RS34575 488800..489090 - 291 WP_162571555.1 ribbon-helix-helix protein, CopG family Antitoxin
E5P2_RS34580 489189..489635 - 447 WP_162571556.1 conjugal transfer protein TraM -
E5P2_RS34585 489635..490360 - 726 WP_162571557.1 conjugal transfer protein TraL -
E5P2_RS34590 490360..490836 - 477 WP_162571558.1 TraK family protein -
E5P2_RS34595 491114..491488 + 375 WP_162571559.1 conjugal transfer protein TrbJ -
E5P2_RS34600 491523..493787 + 2265 WP_162571560.1 relaxase/mobilization nuclease domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..560632 560632


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11187.86 Da        Isoelectric Point: 8.0182

>T288578 WP_162571554.1 NZ_LR594668:c488812-488516 [Variovorax sp. SRS16]
MPRLIWSPHALSDVQRLYRFLCGKNPDAARRAVRTIRDGMMVVAQQPGIGRPIADMEPEYREWLIDFGAGGYVAKYRLDG
ETAVVLAVRHQREVGYEE

Download         Length: 297 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11141.73 Da        Isoelectric Point: 7.4243

>AT288578 WP_162571555.1 NZ_LR594668:c489090-488800 [Variovorax sp. SRS16]
MNTSALRPVTVKIEPSVKLRVQRLAKARHRTPHWVMHEAILQFVEREEKREAFRQDAIRAWDEYRLTGLHVTAAEADAWM
AKLETGQDVEPPECHG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References