Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 7682..8235 Replicon plasmid 3
Accession NZ_LR594668
Organism Variovorax sp. SRS16

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E5P2_RS32200 Protein ID WP_162571164.1
Coordinates 7960..8235 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E5P2_RS32195 Protein ID WP_162571163.1
Coordinates 7682..7963 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5P2_RS32165 3218..3550 + 333 WP_162571158.1 hypothetical protein -
E5P2_RS32170 3705..3998 + 294 WP_162571159.1 hypothetical protein -
E5P2_RS32175 3995..4411 + 417 WP_162571160.1 PIN domain-containing protein -
E5P2_RS32180 4890..5156 + 267 WP_162571161.1 hypothetical protein -
E5P2_RS32185 5153..6994 + 1842 WP_162571621.1 integrase -
E5P2_RS32190 7036..7356 + 321 WP_162571162.1 hypothetical protein -
E5P2_RS32195 7682..7963 + 282 WP_162571163.1 ribbon-helix-helix domain-containing protein Antitoxin
E5P2_RS32200 7960..8235 + 276 WP_162571164.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E5P2_RS32205 8379..9260 + 882 WP_162571165.1 hypothetical protein -
E5P2_RS32210 9452..9850 - 399 WP_162571166.1 hypothetical protein -
E5P2_RS32215 10351..11211 + 861 WP_174262739.1 MaoC family dehydratase N-terminal domain-containing protein -
E5P2_RS32220 11242..12432 + 1191 WP_162571167.1 CoA transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..560632 560632


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10658.28 Da        Isoelectric Point: 10.0843

>T288576 WP_162571164.1 NZ_LR594668:7960-8235 [Variovorax sp. SRS16]
MKVQWTSKALSDLVRLHEFLAAVNGPAAARAIQQLTAAPSKLTINPRIGERLEEFEPREVRRILVGRYEVRYEIQESTIY
VLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10295.63 Da        Isoelectric Point: 5.6643

>AT288576 WP_162571163.1 NZ_LR594668:7682-7963 [Variovorax sp. SRS16]
MAQTAETRVLTAHVPLQLAEKVDQWAARLERSKGWIVKQALTAWIDQEQERSRLTHEALADVDAGQVIDQQAVQAWADSL
GTNAVLPVPAARR

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References