Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 5252913..5253628 Replicon chromosome
Accession NZ_LR594666
Organism Variovorax sp. SRS16

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag E5P2_RS25355 Protein ID WP_162569855.1
Coordinates 5252913..5253365 (-) Length 151 a.a.

Antitoxin (Protein)


Gene name PrcA Uniprot ID -
Locus tag E5P2_RS25360 Protein ID WP_162569856.1
Coordinates 5253365..5253628 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5P2_RS25335 5248212..5249477 + 1266 WP_174262699.1 cation:proton antiporter -
E5P2_RS25340 5249513..5250637 + 1125 WP_162570663.1 glutamate--cysteine ligase -
E5P2_RS25345 5250645..5251628 + 984 WP_162569853.1 thiamine-phosphate kinase -
E5P2_RS25350 5251671..5252831 - 1161 WP_162569854.1 MFS transporter -
E5P2_RS25355 5252913..5253365 - 453 WP_162569855.1 RES family NAD+ phosphorylase Toxin
E5P2_RS25360 5253365..5253628 - 264 WP_162569856.1 DUF2384 domain-containing protein Antitoxin
E5P2_RS25365 5253721..5254647 + 927 WP_162569857.1 LysR family transcriptional regulator -
E5P2_RS25370 5254681..5255382 + 702 WP_162569858.1 phosphatase PAP2 family protein -
E5P2_RS25375 5255379..5255618 + 240 WP_162569859.1 acyl carrier protein -
E5P2_RS25380 5255615..5256817 + 1203 WP_162569860.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-144)

Antitoxin

Antitoxin Xre

(2-87)


Sequences

Toxin        


Download         Length: 151 a.a.        Molecular weight: 16047.52 Da        Isoelectric Point: 9.4319

>T288575 WP_162569855.1 NZ_LR594666:c5253365-5252913 [Variovorax sp. SRS16]
MRVYRISKAVHVATALSGQGAALYAGRWKSRGVRLAYMAGSAALAMLELLVHVDKEDAPTGLRLLSYELPDDAVQPLHAL
PPGWSALPYSPAVQAVGDRWIASGRSLALRVPSAVARHESNVLVNPGHARFAEIALVADETLTLDARLFA

Download         Length: 453 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9854.16 Da        Isoelectric Point: 9.0329

>AT288575 WP_162569856.1 NZ_LR594666:c5253628-5253365 [Variovorax sp. SRS16]
MAIPARTFHRRQQKAETLSATETDRVLRIARVASHAMQVFGSEEKARRWLSRDNRMLGATPLQMLSTDAGAHEVEAELNR
IEFGDFA

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References