288543

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sezT-pezT/zeta-couple_hipB
Location 660726..661984 Replicon chromosome
Accession NZ_LR594050
Organism Streptococcus porcinus strain NCTC10925

Toxin (Protein)


Gene name sezT Uniprot ID -
Locus tag FGL20_RS03305 Protein ID WP_093958852.1
Coordinates 661202..661984 (+) Length 261 a.a.

Antitoxin (Protein)


Gene name pezT Uniprot ID -
Locus tag FGL20_RS03300 Protein ID WP_093958853.1
Coordinates 660726..661202 (+) Length 159 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL20_RS03265 657196..657495 + 300 WP_000194866.1 hypothetical protein -
FGL20_RS03270 657509..657799 + 291 WP_024413658.1 hypothetical protein -
FGL20_RS03275 657895..658533 + 639 WP_044980767.1 hypothetical protein -
FGL20_RS03280 658573..659649 + 1077 WP_093958857.1 toprim domain-containing protein -
FGL20_RS03285 659703..659930 + 228 WP_093958856.1 hypothetical protein -
FGL20_RS03290 659927..660316 + 390 WP_093958855.1 chemotaxis protein -
FGL20_RS03295 660366..660656 + 291 WP_172601694.1 hypothetical protein -
FGL20_RS03300 660726..661202 + 477 WP_093958853.1 helix-turn-helix domain-containing protein Antitoxin
FGL20_RS03305 661202..661984 + 783 WP_093958852.1 zeta toxin family protein Toxin
FGL20_RS03310 661981..663210 + 1230 WP_024380477.1 SIR2 family protein -
FGL20_RS03315 663200..664819 + 1620 WP_024390203.1 ATP-binding protein -
FGL20_RS03320 665203..665565 + 363 WP_000140674.1 hypothetical protein -
FGL20_RS03325 665568..665933 + 366 WP_000431640.1 plasmid mobilization relaxosome protein MobC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(28-215)

Antitoxin

Cro/C1-type helix-turn-helix domain

(3-60)


Sequences

Toxin        


Download         Length: 261 a.a.        Molecular weight: 29612.57 Da        Isoelectric Point: 6.7610

>T288543 WP_093958852.1 NZ_LR594050:661202-661984 [Streptococcus porcinus]
MRLEEFSEAEFQKALQRTIRALTRGKTIPDRPKAILLGGQSGAGKTTIHRIKQKEFQGNIIIIDGDSYRSQHPNYLALQE
KYGKDSVDYTKGFAGKMVEHLIDELSTQGYHLLIEGTLRTTQVPRQTAQLLSSKGYQVSLAVIGTKPELSYLSTLIRYEE
LYAIDPTQARATPKEHHDGIVENLVDNLKELESDKLFDRIQIYQRDRSCIYDSETDEGSAAEVLQDCLFGKWSKVEEGML
QIEKDRLKRLYKVKENGNSL

Download         Length: 783 bp

Antitoxin


Download         Length: 159 a.a.        Molecular weight: 18329.74 Da        Isoelectric Point: 4.4042

>AT288543 WP_093958853.1 NZ_LR594050:660726-661202 [Streptococcus porcinus]
MIGDNIKSLRRTHDLTQPEFAKMVGISRNSLSRYENGTSTVSTELIDRICQKFNVSYVDIVGEDKMLTPVEDYQLTLRIE
VIKERGAAILSQLYRYQDSQDIAFDDESNPWILMSDDLAELINTKIYLVDTFDEIERYNGYLDGIERMLEMVHHRVVA

Download         Length: 477 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References