Detailed information of TA system TA288542

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): abiEi-abiEii/AbiEii-AbiEi
• Location: 642918..644350
• Replicon: chromosome
• Accession: NZ_LR594050
• Organism: Streptococcus porcinus strain NCTC10925

Toxin (Protein)

• Gene name: abiEi
• Uniprot ID: -
• Locus tag: FGL20_RS03230
• Protein ID: WP_093958862.1
• Coordinates: 642918..643763 (-)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: abiEii
• Uniprot ID: -
• Locus tag: FGL20_RS03235
• Protein ID: WP_093958861.1
• Coordinates: 643760..644350 (-)
• Length: 197 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGL20_RS03225	640054..642855	+	2802	WP_093958863.1	CHAP domain-containing protein	-
FGL20_RS03230	642918..643763	-	846	WP_093958862.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
FGL20_RS03235	643760..644350	-	591	WP_093958861.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (33-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-50)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 32448.11 Da
• Isoelectric Point: 5.4360

>T288542 WP_093958862.1 NZ_LR594050:c643763-642918 [Streptococcus porcinus]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLRNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMIRLITVLVSINSD

Nucleotide

• Length: 846 bp

Antitoxin

Protein

• Length: 197 a.a.
• Molecular weight: 23106.65 Da
• Isoelectric Point: 7.8297

>AT288542 WP_093958861.1 NZ_LR594050:c644350-643760 [Streptococcus porcinus]
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRYPKAIFSYISALYL
QQFTDEIPQYFDVTIPRGYRFNTPPANLNIHSVSKEYSELGITLVKTPMGNEVRVYDLERIICDFVIHREKIDTELFVKT
LQHYGNYSKKNLTKLYEYATKMNTLDKVKQTLEVLV

Nucleotide

• Length: 591 bp