Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 2143962..2144448 | Replicon | chromosome |
Accession | NZ_LR594048 | ||
Organism | Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556 |
Toxin (Protein)
Gene name | relE | Uniprot ID | Q48QR0 |
Locus tag | FGL22_RS10565 | Protein ID | WP_014407961.1 |
Coordinates | 2143962..2144231 (-) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A660A1J7 |
Locus tag | FGL22_RS10570 | Protein ID | WP_014407962.1 |
Coordinates | 2144221..2144448 (-) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FGL22_RS10550 | 2139301..2141574 | - | 2274 | WP_046178065.1 | YhgE/Pip domain-containing protein | - |
FGL22_RS10555 | 2141709..2142242 | + | 534 | WP_003059589.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
FGL22_RS10560 | 2142270..2143634 | - | 1365 | Protein_1996 | IS1182 family transposase | - |
FGL22_RS10565 | 2143962..2144231 | - | 270 | WP_014407961.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FGL22_RS10570 | 2144221..2144448 | - | 228 | WP_014407962.1 | hypothetical protein | Antitoxin |
FGL22_RS10575 | 2144585..2144971 | - | 387 | WP_138129493.1 | ArpU family transcriptional regulator | - |
FGL22_RS10580 | 2144946..2145308 | - | 363 | WP_046177962.1 | DUF1492 domain-containing protein | - |
FGL22_RS10585 | 2145547..2145768 | - | 222 | WP_046177979.1 | hypothetical protein | - |
FGL22_RS10590 | 2145768..2146016 | - | 249 | WP_100249571.1 | hypothetical protein | - |
FGL22_RS10595 | 2146006..2146344 | - | 339 | WP_037580661.1 | hypothetical protein | - |
FGL22_RS10600 | 2146415..2146675 | - | 261 | WP_046177963.1 | hypothetical protein | - |
FGL22_RS10605 | 2146685..2147470 | - | 786 | WP_046177964.1 | hypothetical protein | - |
FGL22_RS10935 | 2147560..2147709 | - | 150 | WP_162836006.1 | hypothetical protein | - |
FGL22_RS10610 | 2147723..2147968 | - | 246 | WP_015058152.1 | hypothetical protein | - |
FGL22_RS10940 | 2147943..2148080 | - | 138 | WP_158001818.1 | hypothetical protein | - |
FGL22_RS10945 | 2148082..2148255 | - | 174 | WP_046177965.1 | hypothetical protein | - |
FGL22_RS10615 | 2148261..2148434 | - | 174 | WP_046177966.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 2122064..2173224 | 51160 | |
- | flank | IS/Tn | - | - | 2142543..2143667 | 1124 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10497.50 Da Isoelectric Point: 10.5027
>T288541 WP_014407961.1 NZ_LR594048:c2144231-2143962 [Streptococcus dysgalactiae subsp. equisimilis]
MTYKLVVSDEVKKQLKKMDKHVGLMLAKDMKKRLDGLNNPRQFGKALTGQYKGLWRYRVGNYRVICDIVDNEMIILALEV
GHRKEIYKR
MTYKLVVSDEVKKQLKKMDKHVGLMLAKDMKKRLDGLNNPRQFGKALTGQYKGLWRYRVGNYRVICDIVDNEMIILALEV
GHRKEIYKR
Download Length: 270 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A660A202 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A660A1J7 |