Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 646419..647037 Replicon chromosome
Accession NZ_LR594047
Organism Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGL21_RS03485 Protein ID WP_003058081.1
Coordinates 646419..646760 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGL21_RS03490 Protein ID WP_003058067.1
Coordinates 646750..647037 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL21_RS03465 641882..643126 - 1245 WP_014612120.1 site-specific integrase -
FGL21_RS03470 643137..643334 - 198 WP_003058094.1 transposase -
FGL21_RS03475 643354..644457 - 1104 WP_014612121.1 CHAP domain-containing protein -
FGL21_RS03480 644460..646361 - 1902 WP_003058051.1 hypothetical protein -
FGL21_RS03485 646419..646760 - 342 WP_003058081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL21_RS03490 646750..647037 - 288 WP_003058067.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FGL21_RS03495 647108..649606 - 2499 WP_003058044.1 ATP-binding protein -
FGL21_RS03500 649590..650006 - 417 WP_003058056.1 conjugal transfer protein -
FGL21_RS03505 650015..650233 - 219 WP_003058071.1 hypothetical protein -
FGL21_RS03510 650230..651171 - 942 WP_003058075.1 conjugal transfer protein -
FGL21_RS03515 651184..651447 - 264 WP_003058063.1 hypothetical protein -
FGL21_RS03520 651457..651729 - 273 WP_003058046.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - tufA 599975..720751 120776


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T288536 WP_003058081.1 NZ_LR594047:c646760-646419 [Streptococcus dysgalactiae subsp. equisimilis]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10869.33 Da        Isoelectric Point: 4.3885

>AT288536 WP_003058067.1 NZ_LR594047:c647037-646750 [Streptococcus dysgalactiae subsp. equisimilis]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKDLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References