288533

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 561071..561689 Replicon chromosome
Accession NZ_LR594045
Organism Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGL14_RS03060 Protein ID WP_003058081.1
Coordinates 561071..561412 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGL14_RS03065 Protein ID WP_138083747.1
Coordinates 561402..561689 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL14_RS03040 556534..557778 - 1245 WP_138083745.1 site-specific integrase -
FGL14_RS03045 557789..557986 - 198 WP_003058094.1 transposase -
FGL14_RS03050 558006..559109 - 1104 WP_046177356.1 CHAP domain-containing protein -
FGL14_RS03055 559112..561013 - 1902 WP_138083746.1 hypothetical protein -
FGL14_RS03060 561071..561412 - 342 WP_003058081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL14_RS03065 561402..561689 - 288 WP_138083747.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FGL14_RS03070 561760..564258 - 2499 WP_138083748.1 ATP-binding protein -
FGL14_RS03075 564242..564658 - 417 WP_003058056.1 conjugal transfer protein -
FGL14_RS03080 564667..564885 - 219 WP_003058071.1 hypothetical protein -
FGL14_RS03085 564882..565823 - 942 WP_138083749.1 conjugal transfer protein -
FGL14_RS03090 565836..566099 - 264 WP_003058063.1 hypothetical protein -
FGL14_RS03095 566109..566381 - 273 WP_003058046.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - tufA 497181..631969 134788


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T288533 WP_003058081.1 NZ_LR594045:c561412-561071 [Streptococcus dysgalactiae subsp. equisimilis]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10868.35 Da        Isoelectric Point: 4.4929

>AT288533 WP_138083747.1 NZ_LR594045:c561689-561402 [Streptococcus dysgalactiae subsp. equisimilis]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKNLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References