Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4592699..4593518 Replicon chromosome
Accession NZ_LR594038
Organism Klebsiella grimontii strain NCTC9146 substr. serovar casular

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag FGL39_RS21900 Protein ID WP_004132607.1
Coordinates 4593261..4593518 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag FGL39_RS21895 Protein ID WP_004132606.1
Coordinates 4592699..4593250 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL39_RS21880 4588088..4589485 + 1398 WP_077259852.1 MFS transporter -
FGL39_RS21885 4589609..4590949 + 1341 WP_049099856.1 carbohydrate porin -
FGL39_RS21890 4591053..4592681 - 1629 WP_064363102.1 SAM-dependent methyltransferase -
FGL39_RS21895 4592699..4593250 - 552 WP_004132606.1 N-acetyltransferase Antitoxin
FGL39_RS21900 4593261..4593518 - 258 WP_004132607.1 YjhX family toxin Toxin
FGL39_RS21905 4594102..4595286 + 1185 WP_049085652.1 mannonate dehydratase -
FGL39_RS21910 4595363..4596838 + 1476 WP_024359122.1 fructuronate reductase -
FGL39_RS21915 4596975..4597751 + 777 WP_024359123.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T288522 WP_004132607.1 NZ_LR594038:c4593518-4593261 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT288522 WP_004132606.1 NZ_LR594038:c4593250-4592699 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References