Detailed information of TA system TA288510

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): abiEi-abiEii/AbiEii-AbiEi
• Location: 1100413..1101845
• Replicon: chromosome
• Accession: NZ_LR594036
• Organism: Streptococcus porcinus strain NCTC10710

Toxin (Protein)

• Gene name: abiEi
• Uniprot ID: -
• Locus tag: FGK96_RS05190
• Protein ID: WP_138081998.1
• Coordinates: 1101000..1101845 (+)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: abiEii
• Uniprot ID: -
• Locus tag: FGK96_RS05185
• Protein ID: WP_138081996.1
• Coordinates: 1100413..1101003 (+)
• Length: 197 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGK96_RS05185	1100413..1101003	+	591	WP_138081996.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
FGK96_RS05190	1101000..1101845	+	846	WP_138081998.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
FGK96_RS05205	1102169..1104091	-	1923	WP_138082000.1	group II intron reverse transcriptase/maturase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (33-257)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-50)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 32455.19 Da
• Isoelectric Point: 6.0400

>T288510 WP_138081998.1 NZ_LR594036:1101000-1101845 [Streptococcus porcinus]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFKKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLANVLDEMIHLITVLISINSD

Nucleotide

• Length: 846 bp

Antitoxin

Protein

• Length: 197 a.a.
• Molecular weight: 23160.73 Da
• Isoelectric Point: 7.8272

>AT288510 WP_138081996.1 NZ_LR594036:1100413-1101003 [Streptococcus porcinus]
MSKKEILLEFIENHNGIITYKDCKALNIPTIYLTRLEKEGILYRVEKGIFLTQNGDYDEYYFFQYRYPKAVFSYISALYL
QQFTDEIPQYFDVTIPRGYRFNTPPANLNIHSVSKENSELGITLVKTPMGNEVRVYDFERIICDFVIHREKIDTELFVKT
LQLYGNYPKKNLTKLYEYATKLNTLAKVKQTLEVLV

Nucleotide

• Length: 591 bp