Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/-
Location 1313922..1314537 Replicon chromosome
Accession NZ_LR594035
Organism Streptococcus pseudoporcinus strain NCTC5385

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FGL04_RS06840 Protein ID WP_138068665.1
Coordinates 1313922..1314260 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FGL04_RS06845 Protein ID WP_138068666.1
Coordinates 1314250..1314537 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL04_RS06810 1308970..1309587 - 618 Protein_1317 hypothetical protein -
FGL04_RS06815 1309775..1310880 + 1106 WP_138068165.1 IS3 family transposase -
FGL04_RS06820 1310922..1311293 - 372 Protein_1319 ABC transporter ATP-binding protein -
FGL04_RS06825 1311410..1312016 - 607 Protein_1320 TetR/AcrR family transcriptional regulator -
FGL04_RS06830 1312468..1312821 + 354 WP_138068664.1 plasmid mobilization relaxosome protein MobC -
FGL04_RS06835 1312804..1313361 - 558 WP_138069164.1 replication initiation factor domain-containing protein -
FGL04_RS06840 1313922..1314260 - 339 WP_138068665.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL04_RS06845 1314250..1314537 - 288 WP_138068666.1 XRE family transcriptional regulator Antitoxin
FGL04_RS06855 1316033..1316407 + 375 Protein_1326 DDE-type integrase/transposase/recombinase -
FGL04_RS06860 1316443..1317423 - 981 Protein_1327 glucan-binding protein -
FGL04_RS06870 1317701..1318291 + 591 WP_138068667.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
FGL04_RS06875 1318288..1319133 + 846 WP_138068668.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1306011..1316407 10396
- inside Prophage - - 1272672..1333433 60761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13179.40 Da        Isoelectric Point: 9.8162

>T288506 WP_138068665.1 NZ_LR594035:c1314260-1313922 [Streptococcus pseudoporcinus]
MESKIYEIRYSSQVAQTLLEIRDYIFEISKSENIADKNIEKIIKGIEVLKLFPEAGFNADKKFGKKIDEKRSIRGITLKK
NYIALYDIDDKNFVVNIRYLLATKSDYMKLFK

Download         Length: 339 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10945.53 Da        Isoelectric Point: 4.5308

>AT288506 WP_138068666.1 NZ_LR594035:c1314537-1314250 [Streptococcus pseudoporcinus]
MVVLNQTKMVNFPADRSLADSAKQIMKEQNLSQTEVFNLFLKNIVVTGRINLLSEEELEKERLFKELQSEVKASIAEMEA
GNYYTESQLREYLGI

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References