Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 3128240..3129033 Replicon chromosome
Accession NZ_LR593886
Organism Gemmata massiliana isolate Soil9

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag SOIL9_RS13370 Protein ID WP_162668135.1
Coordinates 3128515..3129033 (+) Length 173 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag SOIL9_RS13365 Protein ID WP_162668134.1
Coordinates 3128240..3128518 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SOIL9_RS13345 3123814..3124377 - 564 WP_162668130.1 hypothetical protein -
SOIL9_RS13350 3124597..3127302 + 2706 WP_162668131.1 relaxase domain-containing protein -
SOIL9_RS13355 3127292..3127723 + 432 WP_162668132.1 hypothetical protein -
SOIL9_RS13360 3127885..3128139 - 255 WP_162668133.1 hypothetical protein -
SOIL9_RS13365 3128240..3128518 + 279 WP_162668134.1 DUF1778 domain-containing protein Antitoxin
SOIL9_RS13370 3128515..3129033 + 519 WP_162668135.1 GNAT family N-acetyltransferase Toxin
SOIL9_RS13375 3129233..3129541 - 309 WP_162668136.1 metalloregulator ArsR/SmtB family transcription factor -
SOIL9_RS13380 3129895..3130347 - 453 WP_162668137.1 hypothetical protein -
SOIL9_RS13385 3130796..3131067 - 272 Protein_2660 type II toxin-antitoxin system ParD family antitoxin -
SOIL9_RS13390 3131269..3131547 - 279 WP_162668138.1 hypothetical protein -
SOIL9_RS13395 3131748..3131996 + 249 WP_162668139.1 helix-turn-helix transcriptional regulator -
SOIL9_RS13400 3132146..3132406 - 261 WP_162668140.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-147)

Antitoxin

Vibrio phage ICP1, Orf50

(9-92)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 18751.74 Da        Isoelectric Point: 8.7517

>T288505 WP_162668135.1 NZ_LR593886:3128515-3129033 [Gemmata massiliana]
MTRGHVSPPALLTDGHDLAPFDCGVPSLNDWLRRRALKNNRSGASRTYVLCNGAVVVGYYCLATGAVYHDDAPHALRRNM
PDPIPVLVLGRLAVDRRCQNQKIGRAMLRDAALRAQEVAESVGVTAIVVHAISEEARRFYVSCGFVESPLQPMTLCLLMA
TLQNTGARLLIS

Download         Length: 519 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10391.73 Da        Isoelectric Point: 4.1730

>AT288505 WP_162668134.1 NZ_LR593886:3128240-3128518 [Gemmata massiliana]
MPDRQAQPPVTISVEARTQQRDLIDKAAERVGLTRSDFVMGAACREAEDVVLDQTYFPLDARAFAEFMALLEHPPAPDER
LYDLMTAQAPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References