Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4334231..4334900 Replicon chromosome
Accession NC_020211
Organism Serratia marcescens WW4

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag SMWW4_RS20210 Protein ID WP_004931681.1
Coordinates 4334231..4334653 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag SMWW4_RS20215 Protein ID WP_004931679.1
Coordinates 4334634..4334900 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMWW4_RS20190 4330158..4331891 - 1734 WP_015378966.1 single-stranded-DNA-specific exonuclease RecJ -
SMWW4_RS20195 4331898..4332614 - 717 WP_004931688.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
SMWW4_RS20200 4332641..4333540 - 900 WP_004931685.1 site-specific tyrosine recombinase XerD -
SMWW4_RS20205 4333647..4334165 + 519 WP_004931683.1 flavodoxin FldB -
SMWW4_RS20210 4334231..4334653 - 423 WP_004931681.1 protein YgfX Toxin
SMWW4_RS20215 4334634..4334900 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
SMWW4_RS20220 4335221..4336213 + 993 WP_015378968.1 tRNA-modifying protein YgfZ -
SMWW4_RS20225 4336252..4336749 - 498 WP_015378969.1 DUF2165 domain-containing protein -
SMWW4_RS20230 4336900..4337574 - 675 WP_015378970.1 hemolysin III family protein -
SMWW4_RS20235 4337758..4338366 + 609 WP_004931670.1 HD domain-containing protein -
SMWW4_RS20240 4338407..4339333 - 927 WP_015378971.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16487.59 Da        Isoelectric Point: 11.0198

>T28850 WP_004931681.1 NC_020211:c4334653-4334231 [Serratia marcescens WW4]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEQG

Download         Length: 423 bp

>T28850 NC_020211:c4334653-4334231 [Serratia marcescens WW4]
GTGGCCCAGTGGCGATGTGATATCCGCATTTCCTGGCGCACCCAGCTGTTTTCACTGTTGACCCACGGCGTTCTGATCCT
GCTGATCCTGATTTCGCCCTGGCCGGAAGGCTTTGGCCCGCTCTGGCTGGTGCTGCTGACGCTGGTGGTGTTTCAGTGCA
TTCGCAGCCAGAAGCGCATCGCCGCGGTGCAGGGCGAGCTGCGGCTGCTGGCGGATCGGCGTTTCAGCTGGCACGGCCGC
GAGTGGCGGCTGGCGAAAAAACCGTGGATGCCGGGTTACGGCATGCTGTTGACGCTGCAGCCGATGGAAGGCAAAAAGCG
CCGCCGGCTGTGGCTGGCTTCCGACTGCATGAGCAAAGAGGAATGGCGCCACCTGCGGCAGCTGTTGCTGTATCCGCCGG
CGGGTGACGGCGAACAAGGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT28850 WP_004931679.1 NC_020211:c4334900-4334634 [Serratia marcescens WW4]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT28850 NC_020211:c4334900-4334634 [Serratia marcescens WW4]
ATGGATATTAACAACAAAGCACGTATTCACTGGGCTTGCCGCCGTGGCATGCGCGAGCTGGACATCTCCATCATGCCGTT
CTTCGAATACGAATACGACAGCCTGAATGATGCGGACAAGGCGCTGTTTATCCGCCTGCTGGAGTGCGACGATCCCGATT
TGTTCAACTGGCTGATGAATCATGGCGCGCCGCAGGACGGCGAGCTGCAGAGAATGGTGACCCTGATCCAAACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References