288494

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 3478722..3479275 Replicon chromosome
Accession NZ_LR590482
Organism Pseudomonas synxantha strain NCTC10696

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FGL41_RS16120 Protein ID WP_057022653.1
Coordinates 3478722..3479015 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGL41_RS16125 Protein ID WP_057022654.1
Coordinates 3479003..3479275 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL41_RS16095 3474163..3474981 + 819 WP_057022648.1 alpha/beta hydrolase -
FGL41_RS16100 3475036..3475422 - 387 WP_057022649.1 DoxX family protein -
FGL41_RS16105 3475503..3476378 - 876 WP_057022650.1 LysR family transcriptional regulator -
FGL41_RS16110 3476490..3477722 + 1233 WP_057022651.1 YbfB/YjiJ family MFS transporter -
FGL41_RS16115 3477719..3478717 + 999 WP_057022652.1 NAD(P)H-quinone oxidoreductase -
FGL41_RS16120 3478722..3479015 - 294 WP_057022653.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL41_RS16125 3479003..3479275 - 273 WP_057022654.1 CopG family ribbon-helix-helix protein Antitoxin
FGL41_RS16130 3479379..3480506 - 1128 WP_057022655.1 alkene reductase -
FGL41_RS16135 3480585..3481262 - 678 WP_057022656.1 type 1 glutamine amidotransferase domain-containing protein -
FGL41_RS16140 3481259..3481888 - 630 WP_057022657.1 TetR/AcrR family transcriptional regulator -
FGL41_RS16145 3482061..3482999 + 939 WP_057022658.1 GlxA family transcriptional regulator -
FGL41_RS16155 3483539..3484045 - 507 WP_172833441.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10844.48 Da        Isoelectric Point: 6.9784

>T288494 WP_057022653.1 NZ_LR590482:c3479015-3478722 [Pseudomonas synxantha]
VPRLIITATALAGLERCRQLLTEKDPQVARRAAQTINSQLLRLESDPNIGRPYDELPELRELVIAFGDAGYVALYRVIPS
ESAVLVLAFRHQREAGY

Download         Length: 294 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10411.61 Da        Isoelectric Point: 6.0787

>AT288494 WP_057022654.1 NZ_LR590482:c3479275-3479003 [Pseudomonas synxantha]
MATSIKIDDDLKHRIQLLAGARQRTAHWIMREALSQYVEREEARESFKQEALSSWKNYLETGLHVTGSEARAWLDTWGTE
QASEPPKCHD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References