Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1945225..1946442 Replicon chromosome
Accession NZ_LR590482
Organism Pseudomonas synxantha strain NCTC10696

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FGL41_RS09120 Protein ID WP_046068824.1
Coordinates 1945225..1945797 (-) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FGL41_RS09125 Protein ID WP_057024963.1
Coordinates 1945885..1946442 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL41_RS09095 1940506..1941477 + 972 WP_057024967.1 amino acid ABC transporter permease -
FGL41_RS09100 1941470..1942243 + 774 WP_057013589.1 amino acid ABC transporter ATP-binding protein -
FGL41_RS09105 1942262..1943185 + 924 WP_057024966.1 ABC transporter substrate-binding protein -
FGL41_RS09110 1943198..1944781 + 1584 WP_057024965.1 FAD-dependent oxidoreductase -
FGL41_RS09115 1944793..1945215 + 423 WP_057024964.1 RidA family protein -
FGL41_RS09120 1945225..1945797 - 573 WP_046068824.1 HD domain-containing protein Toxin
FGL41_RS09125 1945885..1946442 - 558 WP_057024963.1 helix-turn-helix domain-containing protein Antitoxin
FGL41_RS09130 1946693..1947529 - 837 WP_057024962.1 acid phosphatase -
FGL41_RS09135 1947567..1949507 - 1941 WP_057024961.1 hypothetical protein -
FGL41_RS09140 1949606..1950187 + 582 WP_057024960.1 hypothetical protein -
FGL41_RS09145 1950157..1951371 - 1215 WP_057024959.1 DUF1835 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-184)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21287.39 Da        Isoelectric Point: 4.9633

>T288491 WP_046068824.1 NZ_LR590482:c1945797-1945225 [Pseudomonas synxantha]
MDLEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERLDLLLLAQSLDSPLKTEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDADPLFEALRALIDRATEQRLHAAE

Download         Length: 573 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20480.48 Da        Isoelectric Point: 7.8770

>AT288491 WP_057024963.1 NZ_LR590482:c1946442-1945885 [Pseudomonas synxantha]
MPHSLLKPALPGIALRRWRLLHRVKQSHAAQLFNVTQSTISRWESGVQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRALQFTSPLADLMGQSLWRFATQEIQLIEASLEHTGWRETQAPPALEFTTGSNDSSLVP
IRPSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References