Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 1190989..1191629 Replicon chromosome
Accession NZ_LR590482
Organism Pseudomonas synxantha strain NCTC10696

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag FGL41_RS05520 Protein ID WP_043050338.1
Coordinates 1191216..1191629 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag FGL41_RS05515 Protein ID WP_043050337.1
Coordinates 1190989..1191219 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL41_RS05495 1187252..1188211 + 960 WP_057023887.1 LysR family transcriptional regulator -
FGL41_RS05500 1188304..1188951 - 648 WP_057023888.1 HAD-IB family hydrolase -
FGL41_RS05505 1189024..1189185 - 162 Protein_1057 HNH endonuclease -
FGL41_RS05510 1189260..1190510 - 1251 WP_057023889.1 ribonucleotide-diphosphate reductase subunit beta -
FGL41_RS05515 1190989..1191219 + 231 WP_043050337.1 virulence factor Antitoxin
FGL41_RS05520 1191216..1191629 + 414 WP_043050338.1 type II toxin-antitoxin system VapC family toxin Toxin
FGL41_RS05525 1191787..1192056 - 270 WP_046069194.1 DUF2790 domain-containing protein -
FGL41_RS05530 1192454..1194409 + 1956 WP_057023890.1 acetate--CoA ligase -
FGL41_RS05535 1195091..1195876 + 786 WP_057013611.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15127.45 Da        Isoelectric Point: 7.1890

>T288490 WP_043050338.1 NZ_LR590482:1191216-1191629 [Pseudomonas synxantha]
VTTYMLDTCICSFIMRERPECVLERLALEVARSNRIVISAITYAEMRYGQIGKKASPKHKTLVDEFVKRLDEVLPWGLAA
VDATVEVKRSLTGQGSIIGQNDTAIAGHAIAAGCTLVTNNVREFSRVAGLSYEDWVH

Download         Length: 414 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8709.77 Da        Isoelectric Point: 4.7719

>AT288490 WP_043050337.1 NZ_LR590482:1190989-1191219 [Pseudomonas synxantha]
MRTVSIFKNGKNQAIRFPNDMAYEGVGELEITRNGDTITLRPVRPSWGSLRELPKADEDFLQERQDVIGDEGRFNL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References