Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2010965..2011500 Replicon chromosome
Accession NZ_LR590469
Organism Yersinia enterocolitica subsp. enterocolitica strain NCTC12982

Toxin (Protein)


Gene name relE Uniprot ID A0A8B6KW45
Locus tag FGL26_RS09535 Protein ID WP_005172322.1
Coordinates 2010965..2011252 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8B6KUS5
Locus tag FGL26_RS09540 Protein ID WP_005172325.1
Coordinates 2011249..2011500 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL26_RS09515 2006378..2007061 - 684 WP_032902930.1 response regulator transcription factor -
FGL26_RS09520 2007861..2010140 - 2280 WP_005172316.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
FGL26_RS09530 2010361..2010936 - 576 WP_005172319.1 GDP-mannose pyrophosphatase NudK -
FGL26_RS09535 2010965..2011252 - 288 WP_005172322.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL26_RS09540 2011249..2011500 - 252 WP_005172325.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FGL26_RS09545 2011777..2012376 - 600 WP_005172326.1 cytochrome c-type protein NapC -
FGL26_RS09550 2012404..2012871 - 468 WP_005165692.1 nitrate reductase cytochrome c-type subunit -
FGL26_RS09555 2012942..2015437 - 2496 WP_011815828.1 nitrate reductase catalytic subunit NapA -
FGL26_RS09560 2015434..2015700 - 267 WP_005165688.1 chaperone NapD -
FGL26_RS09565 2015690..2016193 - 504 WP_005172332.1 ferredoxin-type protein NapF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - acrB 2007505..2053802 46297


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11076.06 Da        Isoelectric Point: 10.6907

>T288477 WP_005172322.1 NZ_LR590469:c2011252-2010965 [Yersinia enterocolitica subsp. enterocolitica]
MTYIVKFRDEALKEWHKLDKTIQQQFAKKLKKCSENPHIESARLRGIKNGYKIKLRASGFRLVYEVIDGILVVAVVAVGK
RERSEVYKLASDRLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9270.53 Da        Isoelectric Point: 4.3287

>AT288477 WP_005172325.1 NZ_LR590469:c2011500-2011249 [Yersinia enterocolitica subsp. enterocolitica]
MPSVILTDTSASVSELKKNPMATVNAGAGFPVAILNRNQPVFYCVPAELYEQIMEALDDHELARLVNERRNQPLHDIDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A8B6KW45

Antitoxin

Source ID Structure
AlphaFold DB A0A8B6KUS5

References