Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1206173..1206810 Replicon chromosome
Accession NZ_LR590469
Organism Yersinia enterocolitica subsp. enterocolitica strain NCTC12982

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FGL26_RS05630 Protein ID WP_005170069.1
Coordinates 1206406..1206810 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A0T9QJI8
Locus tag FGL26_RS05625 Protein ID WP_005170066.1
Coordinates 1206173..1206406 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL26_RS05605 1203433..1203729 + 297 WP_005170044.1 NINE protein -
FGL26_RS05610 1204000..1205077 + 1078 Protein_1062 phage tail protein -
FGL26_RS05620 1205077..1205691 + 615 WP_005170056.1 tail fiber assembly protein -
FGL26_RS05625 1206173..1206406 + 234 WP_005170066.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FGL26_RS05630 1206406..1206810 + 405 WP_005170069.1 tRNA(fMet)-specific endonuclease VapC Toxin
FGL26_RS21405 1207420..1207596 + 177 WP_005170072.1 hypothetical protein -
FGL26_RS05635 1207802..1208686 + 885 WP_072075853.1 Rpn family recombination-promoting nuclease/putative transposase -
FGL26_RS05640 1208946..1209747 - 802 Protein_1068 IS3 family transposase -
FGL26_RS05645 1209968..1210264 - 297 WP_002211830.1 integration host factor subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14907.16 Da        Isoelectric Point: 7.4667

>T288471 WP_005170069.1 NZ_LR590469:1206406-1206810 [Yersinia enterocolitica subsp. enterocolitica]
MHKYMLDTNIVIYVIKRRPIEVLGRFNANAGRMVISSITLAELLHGVEKSAAPERNLSVVEDFVSRLTVLDYDDKAAIHY
GSIRASLEQKGTPIGVNDLHIAGHARSTGLILVTNNRKEFDRVPGLIVDNWLGE

Download         Length: 405 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8978.95 Da        Isoelectric Point: 5.0351

>AT288471 WP_005170066.1 NZ_LR590469:1206173-1206406 [Yersinia enterocolitica subsp. enterocolitica]
MSQGTIFTNNRTQNVRLPVDMRFPENVKSVTVRAVGNERILSPVENSWDSFFFSSPRVSDDFLTERAEQHQSERELF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9QJI8

References