Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1840229..1840374 Replicon chromosome
Accession NZ_LR588412
Organism Klebsiella pneumoniae strain NCTC9157

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1840265..1840367 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1840229..1840374 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL27_RS09000 1835359..1837419 + 2061 WP_004151449.1 oligopeptidase B -
FGL27_RS09005 1837423..1838082 - 660 WP_002911407.1 exodeoxyribonuclease X -
FGL27_RS09010 1838161..1838391 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FGL27_RS09015 1838504..1838878 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FGL27_RS09020 1838882..1839751 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
FGL27_RS09025 1839768..1840106 + 339 WP_016529031.1 YebY family protein -
- 1840229..1840374 - 146 - - Antitoxin
- 1840265..1840367 + 103 - - Toxin
FGL27_RS25690 1840742..1840885 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FGL27_RS09035 1840990..1841958 - 969 WP_004151446.1 VirK/YbjX family protein -
FGL27_RS09040 1842115..1842768 + 654 WP_080851225.1 protein-serine/threonine phosphatase -
FGL27_RS09045 1842765..1842956 - 192 WP_002911395.1 YebW family protein -
FGL27_RS09050 1843054..1843293 - 240 WP_002911393.1 YebV family protein -
FGL27_RS09055 1843409..1844842 - 1434 WP_138074245.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T288452 NZ_LR588412:1840265-1840367 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT288452 NZ_LR588412:c1840374-1840229 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References